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immune complexes deposit in tissues, causing inflammation and damage

Immune Complex Disease (ICD) occurs when immune complexes—combinations of antigens and antibodies—form in the bloodstream and deposit in various tissues, leading to inflammation and tissue damage. This can result in conditions such as lupus, rheumatoid arthritis, and certain types of vasculitis. The immune system's response to these complexes can cause symptoms ranging from mild to severe, depending on the organs affected.

Related Terms

• Immune System
• Immune Regulation
• Immune Balance
• HLA-DQ
• NLRP1 Inflammasome
• Inflammasome
• NLRP3 inflammasome
• IκB kinase