60 citations
,
February 1992 in “British Journal of Dermatology”
In this study, serum from patients with alopecia areata or universalis did not affect hair growth in transplanted scalp skin grafts on nude mice, despite increased deposition of immunoreactants.
2 citations
,
July 1994 in “Journal of Dermatological Science”
This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected humanscalp hair over extended periods.
Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.
The hair transplant at Eugenix in New Delhi resulted in poor density and texture, with only about 2,500 grafts surviving out of 4,500. The user is considering holding the clinic accountable and exploring options like shaving, using hair fibers, or seeking another transplant.
A user used oral finasteride and minoxidil for hair loss, seeing new hair growth under a microscope but no visible change. Commenters debated if the growth was real hair or fibers, and the user will update every 90 days.
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
Scientists discovered a sugar gel, 2dDR-SA, that increased hair growth in mice. Users discussed its potential, comparing it to other treatments like Minoxidil and finasteride.
What results can you expect from using bicalutamide on your scalp?There is no published human study of bicalutamide applied to the scalp for hair loss, no licensed topical product and no established dose, so no result can be predicted from it. The evidence that exists is for the oral tablet in women, which is a prescription drug requiring liver monitoring and contraindicated in pregnancy.
Is rapamycin safe for long-term use on the scalp, or should it be used in cycles?There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.
Can latanoprost be safely applied to the scalp, or is it only for eyelashes?Latanoprost is not approved for use on the scalp and its safety there has not been established: the only human scalp evidence is one 24-week pilot trial in 16 men, and clinicians flag irritation, skin darkening and unknown absorption over a large area as open risks.
How does capsicum improve scalp circulation and boost growth?Capsaicin dilates blood vessels through TRPV1 activation, so capsicum is expected to raise scalp blood flow, but every human hair-loss study used it inside a multi-ingredient formula — and the strongest one gave it orally, not on the scalp — so its effect on hair by itself is unproven, and it is a known skin irritant.
How does sh-Polypeptide-7 help stimulate hair follicle activity or reduce scalp inflammation?sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.