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GlossaryHistopathological

microscopic examination of tissue to study disease manifestations

Histopathological refers to the microscopic examination of tissue in order to study the manifestations of disease. This process, also known as histopathology, involves analyzing tissue samples under a microscope to identify abnormalities, such as those seen in conditions like alopecia, where hair follicles might show specific patterns of inflammation or damage.

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research Distinguishing Diffuse Alopecia Areata from Pattern Hair Loss Using CD3+ T Cells

19 citations, February 2016 in “Journal of The American Academy of Dermatology”

CD3+ T-cell presence is a reliable marker to tell apart alopecia areata from pattern hair loss.

research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates

157 citations, August 2010 in “Lupus”

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

research Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

15 citations, November 2018 in “Current radiopharmaceuticals”

Melatonin can help prevent and treat skin damage caused by gamma rays.

research Update on Frontal Fibrosing Alopecia

2 citations, April 2017 in “Actas Dermo-Sifiliográficas”

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

research Therapeutic Effect of Finasteride Through Its Antiandrogenic and Antioxidant Role in a Propionic Acid-Induced Autism Model: Demonstrated by Behavioral Tests, Histological Findings and MR Spectroscopy

3 citations, April 2022 in “Neuroscience Letters”

Finasteride may help treat autism by reducing inflammation and oxidative stress.

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community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.