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Glossary Stress Hormones

chemicals released by the body in response to stress

Stress hormones are chemicals released by the body in response to stress, with cortisol and adrenaline being the most well-known examples. These hormones prepare the body to handle stressful situations by increasing heart rate, blood pressure, and energy supplies. Chronic elevation of stress hormones can negatively impact various bodily functions, including immune response and hair growth, potentially leading to conditions like alopecia.

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Research

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research Hair stress hormones in individuals with a recent suicide attempt experiencing a depressive episode

December 2025 in “Neurobiology of Stress”

This study found that individuals with a recent history of suicide attempts exhibited altered DHEA hair levels, suggesting possible dysregulation of the HPA axis as a biopsychosocial feature, and recommends further investigation into hair hormones as potential markers of suicidal crisis and vulnerability.

New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles

research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP₃‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75^NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles

12 citations , April 2020 in “British Journal of Dermatology”

In this study, researchers found that caffeine can counteract stress-induced damage in ex vivo human androgenetic alopecia hair follicles, suggesting it may help prevent stress-related hair loss.

research P-421 ASSOCIATION BETWEEN STRESS-RELATED HORMONE LEVELS IN HAIR AND SUBJECTIVE MENTAL HEALTH IN JAPANESE WORKERS

July 2024 in “Occupational Medicine”

This study found that among Japanese full-time employees, cortisol levels in hair were negatively associated with aversive coping and emotional support-seeking tendencies, while dehydroepiandrosterone levels were linked to job confidence.

research Hair follicle is a target of stress hormone and autoimmune reactions

61 citations , September 2010 in “Journal of Dermatological Science”

This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.

Stressfulness of Medically Indicated Abortion as Reflected by Hair Concentrations of Stress Hormones Cortisol and Testosterone: A Pilot Study

research Stressfulness of Medically Indicated Abortion as Reflected by Hair Concentrations of Stress Hormones Cortisol and Testosterone: A Pilot Study

January 2025

This study found that women undergoing mid-trimester termination of pregnancy exhibited increased cumulative cortisol and testosterone levels in hair samples, higher anxiety, but better stress coping strategies two months post-abortion, suggesting hair testosterone may be linked to emotional vulnerability such as neuroticism during this period.

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Community Join

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community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice

30 upvotes 5 years ago

Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.

community Connection between caffeine and hair loss?

in Product 2 years ago

Caffeine might raise stress hormones, potentially worsening hair loss. Telogen effluvium is often misattributed to minor stressors rather than significant life events.

community Circadian rhythm disruption and its potential impact on hair growth cycles

in Technology 7 upvotes 4 months ago

Poor sleep quality may affect hair growth cycles by disrupting the body's natural clock and stress hormones. The focus should be on improving sleep to support overall health, including hair growth, rather than relying solely on treatments like Minoxidil, finasteride, or RU58841.

community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)

in Research/Science 110 upvotes 11 months ago

Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.

community It's not fair I'm the one who's supposed to have the most hair.

in Satire 78 upvotes 1 year ago

People discussed hair loss treatments, including finasteride, minoxidil, and microneedling, with varying results and concerns about genetics and hormone levels. Some users shared personal experiences with medication dosages and side effects, while others mentioned the impact of stress on hair loss.

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Learn

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learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Azelaic Acid

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

learn Lavender

Is lavender effective for hormonal hair loss or just stress? Lavender may help with stress-related hair loss but has limited evidence for hormonal hair loss.

learn Vitamin B6

Is Vitamin B6 helpful for stress-related or hormonal hair loss? Vitamin B6 may support overall health but lacks strong evidence for preventing hair loss.

learn procapil

Could pairing Procapil with antioxidants be the power combo for stress-induced hair thinning? Procapil combined with antioxidants may effectively combat stress-induced hair thinning.

learn Baricitinib

Can Baricitinib work if my hair loss is from stress or anxiety? Baricitinib is not effective for hair loss caused by stress or anxiety.

learn Vitamin B5

Is Vitamin B5 beneficial for people experiencing stress-related or nutritional hair loss? Vitamin B5 is not proven to help with stress-related or nutritional hair loss.

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas