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research Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination

43 citations , October 2005 in “Molecular and cellular endocrinology”

This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.

research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation

240 citations , April 2011 in “Pigment Cell & Melanoma Research”

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

research Human Hair Follicle and Epidermal Melanocytes Exhibit Striking Differences in Their Aging Profile which Involves Catalase

56 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that the susceptibility of hair follicle melanocytes to oxidative stress as they age may be key in the graying of hair due to reduced catalase expression and activity.

research INTERACTION OF α-MELANOCYTE-STIMULATING HORMONE, MELATONIN, CYCLIC AMP AND CYCLIC GMP IN THE CONTROL OF MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO

53 citations , July 1981 in “Journal of Endocrinology”

In this study, α-MSH and cyclic AMP were found to stimulate melanogenesis in hair follicle cultures, while cyclic GMP and melatonin inhibited melanin production but not tyrosinase activity.

research EFFECTS OF α-MELANOCYTE-STIMULATING HORMONE AND [8-ARGININE]-VASOTOCIN UPON MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO

12 citations , December 1981 in “Journal of Endocrinology”

This study found that α-melanocyte-stimulating hormone increased melanin production in hair follicles of moulting Siberian hamsters, whereas [8-arginine]-vasotocin inhibited melanin production without affecting tyrosinase activity.

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community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

2 upvotes 2 years ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Growing hair witch capsaicin and occasional topical minoxidil

60 upvotes 8 months ago

A user shared their experience using capsaicin from chili peppers and occasional topical minoxidil to promote hair growth, noting noticeable improvements without significant side effects. They previously experienced side effects from dutasteride and minoxidil but found the new regimen effective and manageable.

community What new hair-loss treatments actually look exciting right now (Oct 2025)

171 upvotes 11 months ago

New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

community New Hair Loss Treatment: Adipose Derived Secretomes

18 upvotes 1 year ago

Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

community Forgotten Hair Loss Peptide by L'Oreal: KPV

5 upvotes 2 years ago

KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.

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