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This study found that SMAD2 overexpression in human hair follicle stem cells promoted differentiation and apoptosis while inhibiting proliferation, and Smurf2 upregulation limited mouse wound healing by suppressing the SMAD2/NANOG/DNMT1 axis.

A new hydrogel can kill resistant bacteria and help heal infected burn wounds.

This study observed that fetal hair follicle melanocytes varied in morphology and development stages, with melanosomes undergoing degradation into irregular pigment particles within keratinocytes.

In this study, researchers developed a biocompatible, ROS-responsive hydrogel to deliver miR-665 locally, effectively reducing inflammatory signaling and promoting hair follicle regeneration in an alopecia areata mouse model, offering a promising approach for targeted treatment.

This study found that a newly developed biocompatible hydrogel, responsive to reactive oxygen species, enabled targeted delivery of miR-665, significantly promoting hair regeneration and reducing T-cell infiltration in a mouse model of alopecia areata, suggesting a promising strategy for treating this condition.