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research Platelet-rich Plasma Injection and Lipofilling-assisted Hair Transplantation on Residual Scalp Alopecia Post Aplasia Cutis Congenita Verticis (ACCV)

March 2025 in “International Journal of Trichology”

In this case report, researchers described a treatment for post-aplasia cutis congenita alopecia using follicular unit transplantation, platelet-rich plasma, and fat grafting, which significantly improved hair follicles, skin quality, and sensitivity in the affected scalp area.

research Two cases of aplasia cutis congenita with hair collar signs and macrophage hyperplasia

2 citations , June 2019 in “The Journal of Dermatology”

This report describes two cases of aplasia cutis congenita with hair collar signs and hemangioma, which may suggest neural tube defects, although imaging showed no bone or neural tissue abnormalities.

research Hair loss in infancy and childhood

1 citations , January 2019 in “Paediatrics and Child Health”

This article reviews pediatric hair growth issues, common causes of hair loss in children, and approaches to diagnosis, but presents no new clinical findings.

research An overview on congenital alopecia in domestic animals

32 citations , November 2006 in “Veterinary dermatology”

This review discusses the various forms of congenital alopecia in domestic animals and highlights the need for improved classification due to limited understanding and rarity; it reports no new clinical results.

research Congenital and Hereditary Skin Diseases

January 2018

This chapter reviews fungal skin diseases in goats and their hereditary aspects, but it does not present new experimental results.

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Community Join

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community Another transplant or SMP? (Not balding)

in Transplants 23 upvotes 8 months ago

The user is considering another hair transplant or scalp micropigmentation (SMP) for a congenital bald spot, but previous transplants were less effective due to scar tissue. Suggestions include using hair fibers, changing hairstyles, or doing nothing, as the spot is not very noticeable.

community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 8 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"

in Research/Science 1391 upvotes 1 year ago

Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.

community Hair follicle dermal papilla exosomes

2 upvotes 1 year ago

The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

community Hair follicle cloning is already possible

in Chat 38 upvotes 1 year ago

Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

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Learn

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learn Niacinamide

Does niacinamide support hair follicle nutrition? Niacinamide is a precursor of NAD+, a molecule cells use for energy. Whether it affects hair follicles in people has not been tested.

learn Scalp Micropigmentation

Will scalp micropigmentation damage my existing hair or follicles? Providers say SMP sits above the hair follicles and does not harm them. No study has tested this, and infection or scarring from any tattoo can affect the skin.

learn Sulforaphane

Can sulforaphane protect hair follicles from inflammation and damage? In lab and mouse studies, sulforaphane reduced markers of inflammation and oxidative stress. No human study has tested whether it protects hair follicles.

learn Fluridil

Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men; placebo-controlled for 3 months, then all on fluridil to 9 months) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Hair Transplant

Surgery that moves hair follicles from the back of the scalp to thinning areas

learn SCUBE3

Signalling protein made in the hair follicle

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

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