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GlossaryHaCaT keratinocytes

immortalized human skin cells used in research

HaCaT keratinocytes are a type of human skin cell that has been immortalized, meaning they can divide indefinitely in laboratory conditions. These cells are commonly used in scientific research to study skin biology, wound healing, and diseases like psoriasis and skin cancer because they closely mimic the behavior of normal human skin cells.

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Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

research Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes

9 citations, November 2012 in “Biomolecules & therapeutics”

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations, November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin

196 citations, May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Sebocytes play a key role in controlling androgen levels in human skin.

research Ligand-Independent Regulation of the Hairless Promoter by Vitamin D Receptor

10 citations, February 2008 in “Photochemistry and photobiology”

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

research Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-Induced Inflammation and Oxidative Stress

43 citations, August 2016 in “International Journal of Nanomedicine”

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

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