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    GlossaryHair Growth Mechanisms (hair growth pathways)

    biological processes regulating hair follicle development and cycling

    Hair Growth Mechanisms refer to the biological processes and pathways that regulate the development, growth, and shedding of hair. These mechanisms involve a complex interplay of genetic, hormonal, and environmental factors that influence the hair follicle cycle, which includes the anagen (growth), catagen (regression), and telogen (resting) phases. Understanding these mechanisms is crucial for developing treatments for hair loss conditions like alopecia.

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      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 7 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  8 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.