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    GlossaryGrowth Factor Antagonist

    substance that blocks proteins promoting cell growth

    A Growth Factor Antagonist is a substance that inhibits the action of growth factors, which are proteins that stimulate cell growth, proliferation, and differentiation. By blocking these signals, growth factor antagonists can slow down or stop processes like tissue regeneration or tumor growth, making them useful in treatments for conditions like cancer or excessive scarring.

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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Please explain this Minoxidil phenomena

      in Minoxidil  60 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.