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    Did you mean Gonadotropin-Releasing Hormone Agonists?
    Glossary Gonadotropin-Releasing Hormone Agonists

    medications that initially boost, then suppress, sex hormone production

    Gonadotropin-Releasing Hormone Agonists (GnRH agonists) are medications that mimic the natural hormone GnRH, which regulates the release of other hormones like luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Initially, they increase the production of these hormones, but with continuous use, they suppress their release, leading to reduced levels of sex hormones such as testosterone and estrogen. This makes them useful in treating hormone-sensitive conditions like prostate cancer, endometriosis, and certain types of breast cancer.

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    Research 10 of 1000+

    1. DIAGNOSTIC AND THERAPEUTIC UTILITY OF GONADOTROPHIN-RELEASING HORMONE AGONIST IN POSTMENOPAUSAL HYPERANDROGENISM OF OVARIAN ORIGIN Journal of the ASEAN Federation of Endocrine Societies · 2023
    2. Gonadotrophin-releasing hormone agonist therapy for hirsutism is as effective as high dose cyproterone acetate but results in a longer remission Human reproduction · 1997 · 49 citations
    3. (PNM-35) Recurrent priapism in a sickle cell disease patient treated with gonadotropin-releasing hormone (GnRH) agonists drugs: a case report The Journal of Sexual Medicine · 2026
    4. Clinical and Hormonal Effects of Chronic Gonadotropin Releasing Hormone Agonist Treatment in Polycystic Ovarian Disease* The Journal of Clinical Endocrinology & Metabolism · 1987 · 96 citations
    5. Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5<i>α</i>-Reductase Activity and Androgen Receptor Content* 1989 · 82 citations
    6. Treatment of Hirsutism with a Gonadotropin-Releasing Hormone Agonist (Nafarelin)∗ 1986 · 77 citations
    7. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism. The Journal of Clinical Endocrinology & Metabolism · 1995 · 62 citations
    8. Gonadotropin-Releasing Hormone Agonist Treatment in Postmenopausal Women with Hyperandrogenism of Ovarian Origin The Journal of Clinical Endocrinology & Metabolism · 2011 · 36 citations
    9. Gonadotropin releasing hormone agonist (nafarelin) test to differentiate gonadotropin deficiency from constitutionally delayed puberty in teen-age boys--a clinical research center study. 1995 · 24 citations
    10. Long-Term Suppression of Testosterone After Treatment with a Gonadotropin-Releasing Hormone Agonist in a Woman with a Presumed Testosterone Secreting Ovarian Tumor The Journal of Clinical Endocrinology & Metabolism · 1997 · 19 citations
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