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GlossaryGonadotropin-releasing hormone

regulates release of reproductive hormones from the pituitary gland

Gonadotropin-releasing hormone (GnRH) is a key hormone produced in the hypothalamus of the brain. It regulates the release of two other important hormones from the pituitary gland: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are crucial for reproductive function, including the development of eggs in ovaries and sperm in testes.

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Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission

research Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission

49 citations, April 1997 in “Human reproduction”

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Utilization of Gonadotrophin-Releasing Hormone Analogue to Differentiate Ovarian from Adrenal Hyperandrogenism in Postmenopausal Women

research Utilization of Gonadotrophin-Releasing Hormone Analogue to Differentiate Ovarian from Adrenal Hyperandrogenism in Postmenopausal Women

4 citations, November 2018 in “Endocrinology, Diabetes & Metabolism Case Reports”

GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.

research Effect of the Gonadotrophin-Releasing Hormone Analogue, Goserelin, and Estradiol Replacement on Sebum Excretion Rates and Hair Size in Mildly Hirsute Women

4 citations, January 1991 in “Journal of dermatological treatment”

Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

research Diagnostic And Therapeutic Utility Of Gonadotrophin-Releasing Hormone Agonist In Postmenopausal Hyperandrogenism Of Ovarian Origin

July 2023 in “Journal of the ASEAN Federation of Endocrine Societies”

GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.

research Non-Polycystic Ovary Syndrome–Related Endocrine Disorders Associated with Hirsutism

39 citations, May 2011 in “European Journal of Clinical Investigation”

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

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community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 115 upvotes 2 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community My Estradiol Level on Finasteride

in Research/Science 19 upvotes 1 month ago

Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 127 upvotes 1 year ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 1 year ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community Testosterone is 1600, would taking low dose anti-androgens be a viable treatment option for people who’s T spikes on DHT-blockers?

in Treatment 44 upvotes 1 year ago

The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.

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