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GlossaryGonadotropin-Releasing Hormone Antagonists (GnRH antagonists)

medications that block hormone signals to reduce sex hormone production

Gonadotropin-Releasing Hormone Antagonists (GnRH antagonists) are medications that block the action of GnRH, a hormone responsible for stimulating the release of other hormones like LH and FSH from the pituitary gland. By inhibiting this pathway, GnRH antagonists can reduce the production of sex hormones such as testosterone and estrogen, making them useful in treatments for conditions like prostate cancer, endometriosis, and certain fertility issues.

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research News And Notes

May 2008 in “Trends in Urology Gynaecology & Sexual Health”

Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.

research Triple Hormonal Blockade (ADT3): A Patient’s Perspective

January 2019 in “Oncogen”

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

research Slow Progress in Prostate Cancer

February 2007 in “BJUI”

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

$Ovarian Stromal Hyperthecosis and Hyperandrogenemia Refractory to Hormonal Suppression$

research Ovarian Stromal Hyperthecosis and Hyperandrogenemia Refractory to Hormonal Suppression

2 citations , October 2015 in “Obstetrics and gynaecology cases - reviews”

Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.

research Pharmacological Control of Reproduction in Dogs and Cats

January 2019

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

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community Hey med experts explain this please??

in Research/Science 7 upvotes 5 months ago

Finasteride, dutasteride, saw palmetto, caffeine, spironolactone, acetyltetrapeptides, tea tree oil, hydrocortisone, zinc pyrithione, latanoprost, melatonin, marine protein supplements, PRP, microneedling, and valproate are discussed as treatments for hair loss. DHT reduction and inflammation control are key strategies.

community Guaranteed Way to Revive ALL Follicles. Transition, and then Transition Back & Maintain (for Men)

in Satire 251 upvotes 10 months ago

Transitioning genders humorously suggested for hair regrowth, noting some transgender individuals experience this. Discusses treatments like minoxidil, finasteride, and hormone therapy, but advises against transitioning solely for hair regrowth.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 3 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 129 upvotes 2 years ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 3 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

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