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research Forensic DNA Phenotyping: A Promising Tool to Predict Human Appearance for Forensic Purposes

May 2023 in “GSC biological and pharmaceutical sciences”

Forensic DNA phenotyping is becoming useful for predicting physical traits in criminal investigations but is limited by ethical concerns and incomplete genetic understanding.

research DNA Phenotyping: Current Application in Forensic Science

11 citations, February 2019 in “Research and reports in forensic medical science”

DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.

research Stem Cells in Tissue Engineering

3 citations, January 2014 in “Elsevier eBooks”

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis

research Col4a2-eGFP Mouse Model Reveals the Molecular and Functional Dynamics of Basement Membrane Remodelling in Hair Follicle Morphogenesis

November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life

research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life

19 citations, October 2017 in “The FASEB Journal”

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

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community Fun thought experiment about halting hair loss permamently

in Research/Science 58 upvotes 5 months ago

A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 120 upvotes 4 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 212 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Binding affinity of pyrilutamide!

in Update 169 upvotes 2 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

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