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    Glossary GABAA Receptors

    ion channels in the brain that reduce neuronal excitability

    GABAA receptors, also known as Gamma-Aminobutyric Acid Type A receptors, are a class of receptors in the brain that respond to the neurotransmitter GABA, the primary inhibitory neurotransmitter in the central nervous system. These receptors are ion channels that, when activated, allow chloride ions to enter the neuron, making it less likely to fire and thus reducing neuronal excitability. This mechanism is crucial for regulating brain activity and is a target for various medications, including sedatives, anxiolytics, and anticonvulsants.

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    Research 10 of 658

    1. Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes Pain · 2009 · 44 citations
    2. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    3. Participation of GABAA, GABAB receptors and neurosteroids in toluene-induced hypothermia: Evidence of concentration-dependent differences in the mechanism of action European Journal of Pharmacology · 2012 · 17 citations
    4. Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion Hormones and behavior · 2017 · 14 citations
    5. PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields Brain research · 2017 · 14 citations
    6. Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids Molecular and Cellular Neuroscience · 2016 · 11 citations
    7. Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors Neuroscience letters · 2019 · 5 citations
    8. Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids 2020
    9. Modificazioni nella funzionalità , nell'espressione dei recettori GABAA extrasinaptici e nella plasticità  sinaptica nell'ippocampo di ratto durante la gravidanza e dopo il parto. 2009
    10. Social isolation alters GABAA receptors plasticity and function: effect of voluntary consumption of ethanol Annals of General Psychiatry · 2008
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    Community 3 of 4

    1. What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas Reddit · 25 Jun 2024
    2. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
    3. After praising finasteride on this sub for a while I realised it gave me Brain Fog. I think its related to inhibiting GABA and interferring with mirtazapine (an antidepressant). Reddit · 1 Jan 2020
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