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    Glossary GABAA Receptors

    ion channels in the brain that reduce neuronal excitability

    GABAA receptors, also known as Gamma-Aminobutyric Acid Type A receptors, are a class of receptors in the brain that respond to the neurotransmitter GABA, the primary inhibitory neurotransmitter in the central nervous system. These receptors are ion channels that, when activated, allow chloride ions to enter the neuron, making it less likely to fire and thus reducing neuronal excitability. This mechanism is crucial for regulating brain activity and is a target for various medications, including sedatives, anxiolytics, and anticonvulsants.

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    Research 10 of 544

    1. PR-independent neurosteroid regulation of α2-GABA-A receptors in the hippocampus subfields Brain research · 2017 · 14 citations
    2. Ovarian Cycle‐Related Neurosteroid Regulation of GABA‐A Receptor Subunit Plasticity in the Hippocampus Subfields The FASEB Journal · 2011 · 1 citations
    3. Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice The FASEB Journal · 2008
    4. Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain Journal of neuroscience research · 2017 · 12 citations
    5. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    6. Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain Neuroendocrinology · 2015 · 33 citations
    7. Changes in expression of the δ subunit of the GABA<sub>A</sub>receptor and in receptor function induced by progesterone exposure and withdrawal Journal of Neurochemistry · 2006 · 25 citations
    8. Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation Psychoneuroendocrinology · 2019 · 12 citations
    9. Aqueous extract of Asiasari radix inhibits formalin-induced hyperalgesia via NMDA receptors Journal of Ethnopharmacology · 2009 · 17 citations
    10. Joint Public Review: Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2 2024
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    Community 3 of 4

    1. What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas Reddit · 25 Jun 2024
    2. DHT and 5AR respect post, it's importance within the brain Reddit · 3 Mar 2024
    3. After praising finasteride on this sub for a while I realised it gave me Brain Fog. I think its related to inhibiting GABA and interferring with mirtazapine (an antidepressant). Reddit · 1 Jan 2020
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