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research Differential expression of a gene homologous to a G-α protein gene in neonatal mouse skin during development of hair follicles

5 citations , January 2001 in “Journal of dermatological science”

In this study, researchers found that the G(S)alpha subunit is strongly expressed in neonatal mouse hair follicles, indicating it may play a role in initiating follicle growth.

research Identification of differentially expressed Gnαs and Gnα11 in sheep ( Ovis aries ) skins associated with white and black coat colors

1 citations , January 2016 in “Acta histochemica”

This study found that Gnαs and Gnα11 proteins were significantly more expressed in the skin of black sheep compared to white sheep, suggesting their role in coat color regulation.

research P.1.g.019 RY-023, an inverse agonist at alpha5 GABAA receptors: the influence on spatial memory and spontaneous locomotor activity

August 2008 in “European Neuropsychopharmacology”

RY-023, a specific drug, can improve early stage memory learning without affecting general activity in rats, but it's less effective for later learning stages and doesn't impact memory recall.

research MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: The Potential Involvement of the Wnt/β-Catenin Signaling Pathway

1 citations , July 2024 in “International Journal of Molecular Sciences”

In this study, miR-181a was found to inhibit the proliferation and induction abilities of ovine dermal papilla cells by targeting the GNAI2 gene and affecting the Wnt/β-Catenin signaling pathway, highlighting its role in the regulation of hair follicle growth and development.

research Expression and Distribution of the Guanine Nucleotide-binding Protein Subunit Alpha-s in Mice Skin Tissues and Its Association with White and Black Coat Colors

1 citations , January 2016 in “Asian-Australasian journal of animal sciences”

In this study, the expression of GnÎ±s was significantly higher in black mice compared to white mice, suggesting its potential involvement in coat color formation in mice.

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Community Join

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community Creatine is the opposite of minoxidil !

324 upvotes 11 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community Is creatine’s effect on DHT something to worry about?

6 upvotes 2 years ago

Creatine's impact on hair loss is debated, with some users reporting worsened hair loss and others seeing no effect. The consensus is that creatine does not significantly increase DHT or cause hair loss, but those already experiencing hair loss might be more affected.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 2 years ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Does Creatine Cause Hair Loss? I Did the Science.

6 upvotes 1 year ago

Creatine at 2.5 g/day did not affect DHT levels in the user, suggesting it may not cause hair loss through DHT. The user used minoxidil during the experiment but did not use finasteride or other DHT-reducing medications.

community Minoxidil, low dose Finasteride, Pyrilutamide, Derma Rolling, shampoo... Why?

in Research/Science 11 upvotes 3 years ago

The conversation is about a person's hair loss treatment regimen, which includes Minoxidil, low-dose Finasteride, Pyrilutamide, weekly use of a derma roller, and hair loss shampoo. They chose these treatments to minimize systemic effects and plan to share their results for others' benefit.

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Learn

3 / 801 results

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

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Clinics

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Experts

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