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Glossary Free Androgens

hormones that circulate unbound in the bloodstream

Free androgens are a type of hormone, like testosterone, that circulate in the bloodstream without being bound to proteins. These unbound hormones are biologically active and can directly interact with cells, influencing various bodily functions such as hair growth, muscle development, and reproductive health. Elevated levels of free androgens can contribute to conditions like acne, hirsutism (excessive hair growth), and androgenic alopecia (hair loss).

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Research

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research Defining hyperandrogenaemia according to the free androgen index in Chinese women: a cross-sectional study

19 citations , March 2012 in “Clinical Endocrinology”

This study established a normative free androgen index range of 0.7-6.4 and identified a cut-off value of 6.1 for reproductive-age women in southern China, highlighting hyperandrogenic women's increased metabolic disorder risks.

research Free androgen index (FAI)’s relations with oxidative stress and insulin resistance in polycystic ovary syndrome

14 citations , March 2023 in “Scientific Reports”

This study found that in women with polycystic ovary syndrome, PCOS phenotype and oxidative stress markers were significantly related to free androgen index levels, but insulin resistance was not.

research Vitamin B₃ (niacin), B₆, C, and iron intake are associated with the free androgen index, especially in normoandrogenic polycystic ovary syndrome

10 citations , July 2022 in “Journal of the Turkish-German Gynecological Association”

In this study, micronutrient intake was associated with androgen levels in women with PCOS, with the association more pronounced in NA PCOS compared to HA PCOS groups.

research The value of the free androgen index depends on the phenotype of polycystic ovary syndrome — a single-centre experience

7 citations , August 2019 in “Endokrynologia Polska”

This study reported that women with metabolic PCOS phenotype have free androgen index values approximately twice as high as those with the reproductive phenotype.

research The Diagnostic Value of Free Androgen Index in Obese Adolescent Females with Idiopathic Hirsutism and Polycystic Ovary Syndrome

5 citations , April 2021 in “Journal of Academic Research in Medicine”

In this study, the free androgen index (FAI) was found to be a reliable marker for diagnosing and monitoring adolescent girls with hyperandrogenism, suggesting clinical reference values for PCOS, obesity, and idiopathic hirsutism.

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Community Join

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community Very high free testosterone on dut…

9 upvotes 7 months ago

The user has high free testosterone and is still experiencing hair loss despite taking dutasteride and oral minoxidil for over three years. They are considering adding a topical anti-androgen like RU58841.

community What hormones should I have tested at a minimum before starting a DHT blocker or anti-androgen?

4 upvotes 2 years ago

The conversation is about someone planning to start finasteride or RU58841 for hair loss and wanting to know which hormones to test beforehand. They found a package for testing testosterone, free testosterone, estradiol, and DHT, and are asking if these tests are enough.

community Hair regrow idea: High dose Testosterone + RU58841

in Satire 2 upvotes 4 months ago

Using high doses of testosterone with RU58841 to create an androgen-free environment for hair regrowth is suggested, but concerns about heart health and the effectiveness of this approach are raised. Alternatives like topical estrogen, progesterone, and other treatments like finasteride and dutasteride are discussed.

community 22 year old, losing hair for 1 year

in General 192 upvotes 1 year ago

A 22-year-old male experiencing hair loss suspects androgenetic alopecia (AGA) and possibly telogen effluvium (TE), with a noted improvement in scalp itch after adopting a gluten-free diet. He is advised to consider treatments like finasteride or minoxidil and to check iron and ferritin levels.

community Just got some test results back.

5 upvotes 6 years ago

The user received hormone test results showing normal estradiol and testosterone levels, low SHBG, and normal free androgen index. They are considering starting finasteride but are concerned due to being slightly overweight.

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learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Thymosin Beta 4

learn Beta Polypeptide

learn dehydroepiandrosterone

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