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Did you mean Follicular Differentiation?

Glossary Follicular Differentiation

process where hair follicle cells become specialized for hair growth

Follicular differentiation is the process by which cells in the hair follicle develop into specialized types that contribute to hair growth. This involves the transformation of stem cells into various cell types, such as those forming the hair shaft, inner root sheath, and sebaceous glands, each playing a crucial role in the structure and function of the hair.

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Research

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research Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins

63 citations , July 2006 in “British Journal of Dermatology”

This study found that keratin K17 is induced in the suprabasal layer of psoriatic scalp epidermis during epidermal hyperproliferation, suggesting it is not specific to hair follicles.

research An immunohistochemical study of the apocrine type of cutaneous mixed tumors with special reference to their follicular and sebaceous differentiation

54 citations , May 1999 in “Journal of Cutaneous Pathology”

This study reports various immunophenotypical patterns in apocrine mixed skin tumors, resembling the structures of hair follicles, sebaceous glands, and apocrine glands.

research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes

11 citations , March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that hair loss in an Olmsted syndrome mouse model with a Trpv3 mutation was linked to premature keratinocyte maturation, affecting hair follicle structure and function.

research Black Hair Follicular Dysplasia in Black and White Saluki Dogs: Differentiation from Color Mutant Alopecia in the Doberman Pinscher by Microscopic Examination of Hairs

28 citations , June 1991 in “Veterinary Dermatology”

This study observed that black-haired areas in female Saluki puppies developed hypotrichosis, with dilated hair follicles containing melanin clumps, while white-haired areas remained normal.

research Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro

51 citations , February 2009 in “Journal of dermatological science”

In this study, β-catenin overexpression in human hair outer root sheath cells increased the expression of Pitx2, which activated the follicular differentiation pathway, suggesting Pitx2's potential role as a modulator in hair growth control.

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community a new supplement just released

12 upvotes 8 years ago

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

community What supplements or extra dtuff do you guys do for your hair?

2 upvotes 2 years ago

OP uses multivitamins, collagen, biotin, keratin, omega-3, satin bonnet, dandruff shampoo, oil moisturizer, and sun exposure for hair care. Users suggest adding antioxidants, probiotics, pumpkin seed oil, vitamin D, iron, and dermastamping.

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Clinics

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Hair Transplant
Australian Hair & Scalp Clinics-Hair Regrowth by Herbal Follicular ActivationMelbourne, VIC · AU

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