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learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

Is finasteride safe? In one-year trials most men tolerated finasteride 1 mg, but its risks are not only sexual: US, UK and EU regulators warn of sexual dysfunction, depression and suicidal thoughts, and of sexual and mood symptoms that have continued after stopping, and men also report cognitive, anxiety and physical symptoms. How often lasting problems happen, and how much of that the drug causes, is not known; finasteride is prescription-only and must not be taken, or handled as crushed or broken tablets, by women who are or may be pregnant.
Are there really risks with topical finasteride? Reports on topical finasteride describe scalp irritation and dermatitis as the effects specific to it, and blood levels lower than the oral drug; whether the oral drug's systemic side effects (sexual, mood, suicidal-thought, cognitive and breast/semen effects, some reported to persist after stopping) are genuinely rarer on the topical form has not been measured in a trial powered to answer it. Both forms are prescription-only and contraindicated around pregnancy.
Does stopping finasteride mean losing all progress? Here's what really happens. Studies and the drug label report that finasteride's benefit lasts only while it is taken: after stopping, scalp DHT returns to baseline and hair loss resumes over roughly 6 to 12 months. Plan any stop with the prescriber, but the UK regulator (MHRA, May 2026) advises stopping finasteride 1 mg immediately and contacting a doctor if depression or suicidal thoughts develop.

learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn RU58841

How does RU58841 compare with minoxidil and finasteride? Minoxidil and finasteride (men only) are approved medicines with labels that list their side effects. RU58841 is an unapproved research chemical with no published human trial for hair loss, and a small 2026 study found it reaches the blood after scalp use.

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Community Join

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community There is simply no way to get finasteride in Germany

in Finasteride/Dutasteride 82 upvotes 2 years ago

A user in Germany struggles to get a finasteride prescription despite trying multiple doctors and apps, only receiving minoxidil. Other users suggest alternative sources like Zava.med, EU doctor App, and buying from pharmacies abroad.

community How the FUCK do y'all afford 2.5mg dutasteride if you're in the eu

in Finasteride/Dutasteride 36 upvotes 7 months ago

Dutasteride is expensive in the EU, prompting consideration of buying it from Turkey or using alternatives like finasteride, minoxidil, and bicalutamide. Users discuss challenges in obtaining prescriptions and the affordability of treatments in different regions.

community Finasterid Progress over 1.5 years

151 upvotes 7 months ago

The user shared their progress using finasteride and minoxidil for hair loss, noting initial side effects and improved hair density. They experienced shedding but saw better results after increasing the finasteride dose and undergoing a hair transplant.

community Finasterid+ oral Minoxidil 8 month progress

784 upvotes 8 months ago

The user experienced significant hair shedding initially but saw progress after 8 months using 1.25 mg of oral finasteride and minoxidil. They noticed increased hair growth on their eyelashes, eyebrows, and body, and considered increasing the dosage but decided to maintain the current regimen.

community Finasterid and Beard; My Conclusion

5 upvotes 11 years ago

Finasteride likely does not significantly affect beard growth. Some users report slowed beard growth, but many maintain their beards without noticeable changes.

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Research

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research The potential involvement of cholinergic system in finasteride induced cognitive dysfunction

November 2020 in “Psychoneuroendocrinology”

In this study, repeated finasteride administration was associated with decreased social interaction and cognitive deficits in male rats, potentially linked to changes in cholinergic system activity.

research SYSTEMATIC REVIEW OF PHARMACOTHERAPY STRATEGIES IN THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA

September 2025 in “International Journal of Innovative Technologies in Social Science”

This review highlights that while pharmacotherapy, including biological agents, provides varying but often partial control of hidradenitis suppurativa depending on disease severity, significant challenges and high relapse rates persist, necessitating further research for more effective treatments.

research The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

6 citations , December 2022 in “International Journal of Molecular Sciences”

This review explores the hormonal factors related to hidradenitis suppurativa, emphasizing insulin resistance and pro-inflammatory adipokines, but reports no new clinical findings and suggests further research is needed.

research Early postnatal inhibition of neurosteroid synthesis changes the later-life adverse outcome of neonatal asphyxia in rats

May 2025 in “Neuropharmacology”

This study in neonatal rats found that inhibiting neurosteroid synthesis with finasteride unexpectedly reduced the severity and duration of neonatal seizures following birth asphyxia, maintained cognitive functions, but increased anxiety-like behaviors, highlighting a complex role of neurosteroids in hypoxic-ischemic encephalopathy outcomes.

research Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases

May 2023 in “Journal of Clinical Medicine”

This review article reports recent advancements in understanding, diagnosing, and treating various hair loss conditions, like androgenetic alopecia and alopecia areata, including their genetic factors and new therapeutic options, while also examining the impact of COVID-19 on hair loss.

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