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glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
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4 / 4 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
learn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
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research Central Centrifugal Cicatricial Alopecia
CCCA is a scarring hair loss condition mainly in African descent women, possibly caused by genetics and hairstyling, treated with gentle hair care and medications.
research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study
The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.
research Correlation Between Clinical Features, Biochemical Parameters, and Histopathological Findings in Women with Patterned Baldness: A Study from North India
Patterned hair loss in women is linked to hormonal imbalances and biochemical changes, and should be evaluated for underlying health issues.
research Pathologic Diagnosis of Central Centrifugal Cicatricial Alopecia on Horizontal Sections
Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
research Evaluation of Perifollicular Inflammation of Donor Area During Hair Transplantation in Androgenetic Alopecia and Its Comparison With Controls
Inflammation around hair follicles may worsen hair loss; evaluating and treating it can improve transplant results.
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5 / 214 resultscommunity Is microneedling still worth it if I’m on oral minoxidil?
Microneedling may still be beneficial for those on oral minoxidil due to its effects on tissue repair and blood flow, not just absorption. Some users report mixed results, and the effectiveness of combining microneedling with oral treatments remains debated.
community Quote from Pelage (PP-405) Spokesperson...
Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community How true is the statement: dead follicles don't grow back?
Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.
community Testosterone and hair loss seeming irrelevance
The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.