Response to Pavlović’s Response to Li et al.'s Therapeutic Efficacy of Platelet-Rich Plasma Combining with Microneedling and Topical Minoxidil in Refractory Severe Androgenic Alopecia

The authors address Professor Pavlović's concerns regarding their study on the therapeutic efficacy of combining platelet-rich plasma (PRP) with microneedling and topical minoxidil for treating severe androgenic alopecia. They clarify the methodology, specifically the depth and angle of PRP injections, which are designed to optimize diffusion and minimize pain. The PRP is injected at a depth that allows it to diffuse into the dermis and subcutaneous fat, potentially counteracting microinflammation and fibrosis around hair follicles. The authors express gratitude for the feedback and hope it encourages further research in managing androgenetic alopecia. No conflicts of interest were disclosed.