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research Hyperandrogenism and insulin resistance modulate gravid uterine and placental ferroptosis in PCOS-like rats

104 citations , June 2020 in “Journal of Endocrinology”

This study suggests that in rats, maternal hyperandrogenism and insulin resistance lead to activation of ferroptosis in the gravid uterus and placenta, mediated by different molecular and cellular mechanisms.

research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide

88 citations , February 2008 in “Journal of Medicinal Chemistry”

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

research The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in women

83 citations , April 1992 in “Clinical Endocrinology”

This study found that treatment with cyproterone acetate and ethinyl oestradiol increased hair density in women with diffuse androgen-dependent alopecia, particularly when serum ferritin levels were above 40 μg/l.

research Ferreting out stem cells from their niches

80 citations , May 2011 in “Nature Cell Biology”

This review discusses the progress in identifying stem cells responsible for tissue regeneration and highlights technological advances in tracking their behavior, but reports no new clinical results.

research Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome

53 citations , November 2021 in “Molecular Human Reproduction”

This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.

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community Ferritin, iron and testosterone

4 upvotes 5 months ago

Dutasteride may affect testosterone levels, leading to high ferritin and iron levels, which can cause hair loss. High ferritin might be linked to past heavy drinking or hemochromatosis.

community Low ferritin / normal iron contributing to hair loss?

4 upvotes 2 months ago

Low ferritin can contribute to hair loss despite normal iron levels, and supplementing iron may help improve hair regrowth when using finasteride. Minoxidil might also aid in recovery, and optimal ferritin levels for hair growth are suggested to be 100+ ng/ml.