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Comparison of 1064-nm Nd:YAG Picosecond Lasers Using Fractional Micro-Lens Array vs. Ablative Fractional 2940-nm Er:YAG Lasers for the Treatment of Atrophic Acne Scar in Asians: A 20-Week Prospective, Randomized, Split-Face, Controlled Trial

research Comparison of 1064-nm Nd:YAG Picosecond Lasers Using Fractional Micro-Lens Array vs. Ablative Fractional 2940-nm Er:YAG Lasers for the Treatment of Atrophic Acne Scar in Asians: A 20-Week Prospective, Randomized, Split-Face, Controlled Trial

April 2023 in “Journal of Investigative Dermatology”

Both laser treatments improved acne scars similarly, but the Nd:YAG laser was safer and less painful, while the Er:YAG laser left patients slightly more satisfied.

Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

April 2016 in “Journal of Investigative Dermatology”

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit

research The Distribution of Estrogen Receptor Beta Is Distinct to That of Estrogen Receptor Alpha and the Androgen Receptor in Human Skin and the Pilosebaceous Unit

130 citations, June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

research Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor Beta Gene Are Associated with Androgen Levels in Women

93 citations, June 2001 in “The Journal of Clinical Endocrinology and Metabolism”

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing

research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing

23 citations, September 2015 in “International Journal of Molecular Medicine”

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

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Community Join

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community Would Fluridil and Alfatradiol work effectively in conjunction with each other?

in Treatment 8 upvotes 4 years ago

Whether using both Fluridil and Alfatradiol together could be more effective than either one alone as a hair loss treatment, given their different mechanisms of action.

community 2-month progress: Ket 3x a week, Min 2x a day, Dut 0.5 every other day, Vit D 125mcg daily, and PRP once a month.

in Progress Pictures 463 upvotes 3 years ago

User's 2-month progress with hair loss treatment includes Ket 3x a week, Min 2x a day, Dut 0.5 every other day, Vit D 125mcg daily, and PRP once a month. Users discuss treatment effectiveness, side effects, and alternative solutions.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 6 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community Shiseido/Replicel RCH-01 trial results were finally shared online

in Treatment 42 upvotes 4 years ago

The Shiseido/Replicel RCH-01 trial results were disappointing and ineffective. Users expressed skepticism and frustration, suggesting alternatives like Tsuji or simply accepting baldness.

community Ashton Kutcher talked about on the tonight show how he was quitting dut. Looks like the Norwood reaper has already come to collect.

in Satire 623 upvotes 1 year ago

The conversation is about Ashton Kutcher's hairline and how some people think it looks good for his age, while others criticize it. Some mention that he used to use medication for hair loss but stopped.

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