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    GlossaryDrug Discovery (Drug Development)

    process of finding new medications for treating diseases

    Drug Discovery, also known as Pharmaceutical Discovery, is the process by which new candidate medications are discovered. It involves identifying active compounds, conducting preclinical research, and optimizing these compounds for efficacy and safety before they can be tested in clinical trials. This complex and multi-step process aims to develop new treatments for diseases, including conditions like alopecia.

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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community discouraged about pyrilutamide

      in Research/Science  11 upvotes 2 years ago
      Discouragement regarding Pyrilutamide, a drug in development for hair loss, and the potential side effects of Finasteride. People discussed anecdotal experiences with Pyrilutamide as well as suggestions to wait out Phase 3 trials before making any conclusions.

      community Information regarding Kintor’s GT20029

      in Product  40 upvotes 2 years ago
      The conversation discusses skepticism about the effectiveness of new hair loss treatments, mentioning that despite 40 years of research, only accidental discoveries like Minoxidil and Finasteride have been made. It also notes that drug development is a slow process, often taking a decade or more to bring a new drug to market.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  3 upvotes 3 months ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.