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GlossaryPreclinical Studies (Preclinical Research)

laboratory and animal tests before human clinical trials

Preclinical Studies, also known as Preclinical Research or Preclinical Testing, are a phase of research conducted before clinical trials in humans. These studies involve laboratory experiments and animal testing to evaluate the safety, efficacy, and biological activity of a new drug or treatment. The goal is to gather enough data to determine whether the treatment is safe and promising enough to move on to human trials.

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research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart

47 citations, May 2020 in “Cardiovascular Research”

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

research Present Chemotherapy-Induced Alopecia and Future Research

November 2021 in “Austin therapeutics”

Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.

research The Role of 3Rs in the Age of One Health: Where We Are and Where We’re Going

October 2023 in “Biomedical science and engineering”

Innovative methods are reducing animal testing and improving biomedical research.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations, January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain

50 citations, May 2019 in “Drugs”

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

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community More great news about SCUBE3... this could be it!

in Research/Science 29 upvotes 1 year ago

SCUBE3 is a potential hair loss treatment that people are hopeful about. It may provide a solution without the side effects of finasteride.

community Injections of follistatin and growth factors shown to improve hair growth in study

6 upvotes 12 years ago

Injections of follistatin and growth factors can improve hair growth. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

community Thoughts and Opinions on upcoming hairloss treatments?

in Chat 11 upvotes 9 months ago

The conversation is about optimism for new hair loss treatments like Stemson's bioengineering, osteopotin, SCUBE3, GT20029, and Verteprofin, and inquires about other notable treatments.

community Whoever had success with PYRILUTAMIDE, please give us hope outside of 5AR inhibitors.

in Product 6 upvotes 4 months ago

Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.

community Why Is Only Tressless Talking About Verteporfin? Healing Wounds With Zero Scarring Has Gargantuan Implications For All of Medicine. So What Gives?

in Research/Science 19 upvotes 2 years ago

The potential of verteporfin to heal wounds without scarring; however, despite its promising preclinical trials and coverage from a major media outlet, there is still no official clinical trial result and the drug has only garnered attention from hair loss communities.

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