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Glossary Laser-Assisted Drug Delivery

uses laser energy to enhance drug absorption through skin

Laser-Assisted Drug Delivery (LADD) is a technique that uses laser energy to create microchannels in the skin, enhancing the penetration and absorption of therapeutic drugs. This method can improve the efficacy of treatments for various conditions, including skin disorders and hair loss, by allowing medications to reach deeper layers of tissue more effectively than traditional topical applications.

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Research

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research Laser-Assisted Drug Delivery: A Systematic Review of Safety and Adverse Events

21 citations , December 2022 in “Pharmaceutics”

This review found that laser-assisted drug delivery in humans was associated with several adverse effects, but no life-threatening events were reported in the studies examined.

research Lessons Learned from the First Decade of Laser-Assisted Drug Delivery

17 citations , January 2021 in “Dermatology and Therapy”

This review discusses laser-assisted drug delivery for enhancing topical treatment efficacy in various dermatological and medical applications but reports no new clinical results, emphasizing the need for further research to optimize its use.

research Fractional non-ablative laser-assisted drug delivery leads to improvement in male and female pattern hair loss

15 citations , February 2018 in “Journal of Cosmetic and Laser Therapy”

This study observed hair regrowth and increased density in four cases of androgenetic alopecia treated with a non-ablative erbium glass fractional laser and topical finasteride, with no significant side effects reported.

research Laser-assisted drug delivery for the treatment of androgenetic alopecia: ablative laser fractional photothermolysis to enhance cutaneous topical delivery of platelet-rich plasma — with or without concurrent bimatoprost and/or minoxidil

9 citations , January 2019 in “Dermatology Online Journal”

In this study, researchers suggest that laser-assisted drug delivery could enhance the administration of platelet-rich plasma, and potentially bimatoprost or minoxidil, for patients with androgenetic alopecia by ensuring uniform placement in the dermis without injection pain.

research 41949 Raman spectroscopy of alopecia drugs to assess their potential for laser-assisted drug delivery

September 2023 in “Journal of The American Academy of Dermatology”

This review discusses the use of Raman spectroscopy to evaluate drug penetration in alopecia treatments and suggests it may be a promising tool for enhancing the effectiveness of laser-assisted drug delivery.

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community Finasteride - 5 years and my expierience

128 upvotes 2 weeks ago

A 26-year-old shared their 5-year experience using finasteride and minoxidil for hair loss, noting initial improvements but later experiencing reduced libido and erection quality, leading them to switch from oral to topical finasteride. They advise starting with a low-dose topical solution and emphasize making informed decisions, acknowledging that while finasteride is effective, it can have side effects.

community IVF process on Finasteride and effects of stopping finasteride.

138 upvotes 9 months ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community Oral Minoxidil Secret Very important

in Minoxidil 237 upvotes 1 year ago

Oral minoxidil can cause side effects like shortness of breath and constipation, which may be reduced by taking it in the morning. Some users experience no side effects, while others switch to topical treatments or adjust their dosage and timing to manage symptoms.

community 0-5 months and losing hope. all oral. 5mg min, 1.1mg fin, 1mg biotin daily

in Is this regrowth? 8 upvotes 9 months ago

The user is experiencing hair loss and is using oral treatments including 5mg minoxidil, 1.1mg finasteride, and 1mg biotin daily. They are considering adding dutasteride and possibly a hair system, while others suggest patience and additional treatments like microneedling.

community Why so much hate for PP405 all of a sudden?

in Technology 48 upvotes 1 year ago

PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.

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