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Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment

research Platelet‐rich plasma for androgenic alopecia: A randomized, placebo‐controlled, double‐blind study and combined mice model experiment

6 citations , March 2021 in “Journal of Cosmetic Dermatology”

In this study, platelet-rich plasma treatment improved hair regrowth and characteristics in mice and showed therapeutic efficacy in Chinese patients with androgenetic alopecia.

$Experimental Confirmation of a Distinctive Diffraction Pattern in Hair From Women With Breast Cancer$

research Experimental Confirmation of a Distinctive Diffraction Pattern in Hair From Women With Breast Cancer

17 citations , June 2001 in “Journal of the National Cancer Institute”

A specific hair diffraction pattern may indicate breast cancer if tested with the correct method.

research Alopecia areata update

244 citations , January 2010 in “Journal of the American Academy of Dermatology”

This review discusses treatment options for alopecia areata and suggests tailored treatment plans, noting the challenges posed by spontaneous remission and limited high-quality clinical trials.

research Effect of a sphingolipid‐mimetic compound on the promotion of hair growth: A randomized, double‐blind, placebo‐controlled clinical trial

6 citations , November 2019 in “Journal of Cosmetic Dermatology”

This study found that applying a 1% BOI lotion improved hair density and thickness in patients with mild pattern hair loss over six months.

Evaluation of Efficacy of Water-Soluble Fraction of Rhus Semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study

research Evaluation of Efficacy of Water-Soluble Fraction of Rhus semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study

April 2025 in “Antioxidants”

In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.

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Community Join

5 / 680 results

community An Experiment Using Microneedling and Essential Oils & Vitamins

9 upvotes 5 years ago

A user is trying to reverse hair loss using vitamins E and D, jojoba oil, rosemary oil, peppermint oil, and microneedling, avoiding finasteride and minoxidil. They plan to use Alpecin shampoo and will provide updates on the effectiveness of this regimen.

community Does Creatine Really Increase DHT? My Personal Experiment

115 upvotes 1 year ago

Creatine does not increase DHT levels, but some report hair loss when using it, possibly due to other factors. The effects on hair loss vary individually, with no clear connection established.

community Been off Tressless for a few years - what’s the latest on GT20029?

17 upvotes 1 month ago

GT20029 is an experimental topical treatment for male-pattern hair loss, showing promising results in Phase 2 trials and moving towards Phase 3. It aims to degrade androgen receptors in hair follicles, differing from treatments like finasteride and minoxidil.

community Which 2026 hair‑loss treatments have the strongest evidence so far? (minoxidil/finasteride vs. clascoterone, PP405, Re:You’s NV‑623/624, AMP‑303, RU58841)

44 upvotes 3 months ago

Minoxidil and finasteride are the only FDA-approved treatments for androgenetic alopecia, while newer treatments like clascoterone, PP405, NV-623/624, AMP-303, and RU58841 are still experimental with varying levels of evidence. Clascoterone shows the most promise due to strong human data, while AMP-303 has notable early human trial results; RU58841 lacks human data and remains experimental.

community Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results

in Update 415 upvotes 1 year ago

ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.

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Learn

4 / 801 results

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Thymosin Beta 4

learn Fluridil

How long does it take to see results with Fluridil in progressive hair loss? No published study measures how long fluridil takes to show a visible change; the single double-blind trial (43 men, 2% fluridil) reported a rise in the proportion of hairs in the growth phase at three and nine months, and community reports describe stabilization rather than regrowth.
Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men, 9 months, double-blind and placebo-controlled) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.

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