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research The Use of Polyethylenimine–DNA to Topically Deliver hTERT to Promote Hair Growth

17 citations, May 2011 in “Gene Therapy”

Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.

research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy

February 2023 in “Materials today bio”

The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.

research Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid

23 citations, January 2014 in “Molecular Therapy”

Applying a special DNA plasmid to the skin can make it thicker and stronger.

research Fidelity of the Human Mitochondrial DNA Polymerase

101 citations, September 2006 in “Journal of Biological Chemistry”

Human mitochondrial DNA polymerase makes very few errors, crucial for preventing degenerative diseases.

research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility

97 citations, March 2002 in “Molecular and cellular biology”

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Wtf have we been doing for the last 30 years

in Treatment 526 upvotes 4 days ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community 3 and a half month progress pic

in Progress Pictures 259 upvotes 1 month ago

The user shared a 3.5-month hair regrowth update using finasteride, 5% topical minoxidil, micro-needling, and keto shampoo, along with lifestyle changes like reducing stress and improving diet. They encourage others to stay committed to their regimen despite initial slow progress.

community Wish me luck,i hope these will help ne regrow my hair

in Minoxidil 8 upvotes 8 months ago

A user hopes to regrow hair using a routine of Min/fin solution twice daily, dermarolling twice weekly, multivitamins daily, and biotin twice daily. Another user doubts the effectiveness of biotin and multivitamins.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

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