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research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia

59 citations, May 2014 in “Expert Opinion on Therapeutic Targets”

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer

17 citations, January 2015 in “MedChemComm”

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

research Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing

28 citations, April 2023 in “Stem cell research & therapy”

Tiny vesicles from stem cells could be a new treatment for healing wounds.

research Risks of Skin, Hair, and Nail Supplements

7 citations, October 2020 in “Dermatology practical & conceptual”

Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.

research The Impact of Sulforaphane on Sex-Specific Conditions and Hormone Balance: A Comprehensive Review

January 2025 in “Applied Sciences”

Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

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Community Join

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community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

in Chat 6 upvotes 4 months ago

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

community 1 month of finasteride sky high estradiol

in Update 7 upvotes 9 months ago

The user reported high estradiol levels after one month of using finasteride for hair loss. They discussed potential side effects and adjustments to their treatment plan.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 5 months ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community How insane is this oral min shed?

in Progress Pictures 111 upvotes 1 year ago

A user started taking 0.625mg oral minoxidil daily for hair loss, increased the dose to 1.25mg, and experienced a significant shed, losing 70% of scalp density. They cannot tolerate finasteride due to side effects but are hopeful for hair regrowth despite the shedding.

community What to do about High E2 levels on Finasteride?

in Treatment 6 upvotes 2 years ago

User experienced high E2 levels after taking finasteride and sought advice on lowering E2 with supplements like Tonkat ali, Fadogia, and Boron. They also used DIM, zinc, and magnesium but avoided using an AI.

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