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    GlossaryDHT Inhibition (DHT suppression)

    reducing dihydrotestosterone to prevent hair loss

    DHT inhibition refers to the process of reducing the activity or production of dihydrotestosterone (DHT), a hormone derived from testosterone. DHT is known to contribute to hair loss, particularly in conditions like androgenetic alopecia (male or female pattern baldness). By inhibiting DHT, treatments aim to slow down or prevent hair loss and promote hair regrowth.

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      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

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      community Efficacy and Systemic DHT Suppression of Topical Finasteride vs Dutasteride

      in General  122 upvotes 1 week ago
      Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 1 year ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 9 months ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.