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GlossaryCytokeratins

fibrous proteins providing structural support in epithelial cells

Cytokeratins, also known as keratin proteins or CKs, are a group of fibrous structural proteins that form the intermediate filaments in epithelial cells. They provide mechanical support and help maintain the integrity of cells and tissues. In a clinical context, cytokeratins are often used as biomarkers in the diagnosis and study of various cancers, as their expression patterns can indicate the type and origin of a tumor.

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research Transgenic Mouse Models Support HCR as an Effector Gene in the PSORS1 Locus

37 citations , June 2004 in “Human molecular genetics online/Human molecular genetics”

The HCR gene contributes to psoriasis risk.

research British Hair and Nail Society

July 2018 in “British Journal of Dermatology”

Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.

Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth in a Randomized Clinical Trial

research Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth in a Randomized Clinical Trial

27 citations , September 2017 in “Journal of Medicinal Food”

Annurca apple supplement safely increases hair growth and keratin in humans.

research Growth Factors Specifically Alter Hair Follicle Cell Proliferation and Collagenolytic Activity Alone or in Combination

56 citations , December 1990 in “Differentiation”

Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.

research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells

835 citations , October 2008 in “Nature Genetics”

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

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