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GlossaryCytokeratins

fibrous proteins providing structural support in epithelial cells

Cytokeratins, also known as keratin proteins or CKs, are a group of fibrous structural proteins that form the intermediate filaments in epithelial cells. They provide mechanical support and help maintain the integrity of cells and tissues. In a clinical context, cytokeratins are often used as biomarkers in the diagnosis and study of various cancers, as their expression patterns can indicate the type and origin of a tumor.

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research Transgenic Mouse Models Support HCR as an Effector Gene in the PSORS1 Locus

37 citations, June 2004 in “Human molecular genetics online/Human molecular genetics”

The HCR gene contributes to psoriasis risk.

research British Hair and Nail Society

July 2018 in “British Journal of Dermatology”

Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.

research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells

13 citations, December 2019 in “Nutrients”

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth in a Randomized Clinical Trial

research Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth in a Randomized Clinical Trial

27 citations, September 2017 in “Journal of Medicinal Food”

Annurca apple supplement safely increases hair growth and keratin in humans.

research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells

835 citations, October 2008 in “Nature Genetics”

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

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