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GlossaryCRISPR (CRISPR technology)

gene-editing tool that precisely alters DNA sequences

CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing technology that allows scientists to precisely alter DNA sequences within organisms. It utilizes the Cas9 protein to cut DNA at specific locations, enabling the addition, removal, or modification of genetic material, which has vast implications for treating genetic disorders, improving crops, and advancing biological research.

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research Progress in Research and Prospects for Application of Precision Gene-Editing Technology Based on CRISPR-Cas9 in the Genetic Improvement of Sheep and Goats

March 2024 in “Agriculture”

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

research CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa

June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Scientists created cell lines to study a genetic skin disorder using CRISPR technology.

research CRISPR/Cas9: A Promising Approach for Alopecia

January 2024 in “Biomedical journal of scientific & technical research”

CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.

research CRISPR-Cas9: A History of Its Discovery and Ethical Considerations of Its Use in Genome Editing

149 citations , August 2022 in “Biochemistry (Moscow)”

CRISPR-Cas9 allows precise DNA editing but raises ethical concerns about modifying human embryos.

research Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers

104 citations , October 2016 in “PLoS ONE”

CRISPR/Cas9 gene editing in cashmere goats increases hair follicles and fiber length, boosting cashmere yield.

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community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 year ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 23 upvotes 4 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

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