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GlossaryProtease

enzyme that breaks down proteins into smaller peptides

A protease, also known as a proteinase or peptidase, is an enzyme that breaks down proteins into smaller peptides or amino acids by cleaving the peptide bonds between amino acids. These enzymes play crucial roles in various biological processes, including digestion, immune response, and cell regulation.

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community Adrogens and Covid-19

in Treatment 7 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.

Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Kintor's email response to me, regarding false advertising, and my proposal for them to develop a topical dut formulation with meaningful efficacy.

in Treatment 46 upvotes 4 months ago

Kintor apologized for using misleading images in their advertisements and promised stricter review processes. They are also considering developing a topical dutasteride formulation.

community The Korean began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor)

in Research 86 upvotes 3 weeks ago

Cold shock therapy may promote hair growth by stimulating follicular muscles and affecting stem cells. The exact mechanisms and full range of elements involved are not yet fully understood.

community how bad it is using a derma roll 1mm everyday with nanoxidil?

in Treatment 1 year ago

Using a 1mm derma roller every day with nanoxidil is not recommended; it should be used once a week. The user had no initial instructions and used it nightly for two months.

community Pyrilutamide ,the molecule’s true nature

in Research 302 upvotes 4 months ago

Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 7 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community Taurine supplements work for hair growth?

in Product 8 upvotes 7 months ago

The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

community Help with female pattern baldness

in Female 10 upvotes 1 year ago

A user discusses their struggle with female pattern baldness, mentioning that Minoxidil helped initially but their hair health declined after stopping a specific diet. They seek advice on managing oily, brittle hair and mention using an egg yolk and olive oil mixture as a temporary solution.

community Optimal dose for topical Melatonin

in Treatment 6 upvotes 1 year ago

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

community Dr. Bloxham's Verteporfin Trial

in Research/Science 30 upvotes 1 year ago

Dr. Bloxham's trial is testing verteporfin on hair transplant patients to see if it can improve hair regrowth in treated areas. People are discussing the potential for follicle regeneration, expected results timeline, and concerns about side effects like cancer.

community Topical spironolactone - anti androgen

in Research/Science 10 upvotes 2 years ago

User asks about topical spironolactone experience. Two studies show it as promising anti-androgen treatment, with 5% cream available on Minoxidilmax website.

community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community 6 months, Derma, Hims Minox/fin topical, RU, Oils, keto/ Hims shampoo

in Progress Pictures 62 upvotes 2 years ago

A user's progress with hair loss treatments such as derma pen, minoxidil/finasteride topical, RU58841, oils and Hims shampoo over 6 months. The replies are full of encouragement for continued progress.

community My 3 months of progress on Fin (oral) + Min (foam)

in Progress Pictures 527 upvotes 2 years ago

User shared 3 months progress using Fin (oral) and Min (foam) for hair loss. Others suggested adding derma rolling and discussed dosages and experiences.

community started using minoxidil and my hair fall has stopped almost completely

in Minoxidil 24 upvotes 5 years ago

A user started using minoxidil and noticed a significant reduction in hair fall after two days. Other users expressed skepticism, suggesting that results typically take longer and may initially increase hair shedding.

community Things I use to reverse my Hair Loss

in Advice 13 upvotes 5 years ago

The user uses finasteride, minoxidil, Nizoral, and dermarolling along with various supplements, oils, and shampoos to combat hair loss. They adjusted their routine based on feedback, changing dermarolling to once a week and reducing zinc intake due to side effects.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 month ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Cure/better treatment options in the future

in Chat 11 upvotes 4 months ago

The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.

community Guys maybe high cholesterol and hair loss are related

in Chat 6 months ago

High cholesterol may accelerate hair loss by reducing blood flow and increasing DHT levels. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 35 upvotes 8 months ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community 2 month progress with Minoxidil and Dermaroller

in Minoxidil 412 upvotes 10 months ago

The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

community TDM-105795 phase 2 results are in!

in Research/Science 28 upvotes 10 months ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community My conclusive research on Hairline and most other facets of appearance

in Research/Science 11 months ago

The user emphasizes hydration, androgen receptors, and a 7-day ejaculation recovery period for appearance enhancement. They suggest Minoxidil, finasteride, and RU58841 for hair loss, along with a diet rich in animal fats, specific exercises, and fasting.

community Have you tried Biotin supplements for your hair?

in Product 25 upvotes 1 year ago

People shared that Biotin supplements did not improve their hair loss and some experienced stronger nails or more pimples. They suggested trying finasteride or minoxidil instead for hair loss treatment.

community 5 months oralfin, topmin, dermarolling

in Progress Pictures 858 upvotes 1 year ago

The user "ninezske" shared their progress pictures of hair regrowth after using oral finasteride, topical minoxidil, and dermarolling. Other users commented on the results and discussed the effectiveness of minoxidil and finasteride.

community Testosterone before and after take fin/dut

in Finasteride/Dutasteride 239 upvotes 1 year ago

User experienced 100% testosterone increase after using Finasteride and Dutasteride for hair loss. Some users discuss potential side effects and reasons for the increase.

community 18->24 six years of Fin and Minox…. I guess we can’t all be winners 😭

in Progress Pictures 572 upvotes 2 years ago

A user named "EgyptStar81" who has been dealing with hair loss since age 15 due to genetics, chemotherapy and finasteride/minoxidil treatment. Possible solutions such as dutasteride, oral minoxidil, hair transplants and extensions were suggested.

community Loosing your hair (young) feels like loosing your identity. Ain’t it right?

in Satire 2 years ago

The emotional and psychological impact of hair loss in young people, how to cope with it, and potential treatments such as finasteride, RU58841, Minoxidil, SMP, and hair transplants.

community The Importance of Not Rushing Your Treatment Protocol

in Treatment 10 upvotes 2 years ago

Taking a slow and steady approach to treating hair loss, as well as the potential risks of combining too many treatments. The post suggests trialling individual treatments (such as Minoxidil, finasteride, or RU58841) for an extended period before adding more into your treatment protocol.