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    GlossaryImmune-Mediated Alopecia

    immune system attacks hair follicles, causing hair loss

    Immune-Mediated Alopecia (IMA) is a condition where the body's immune system mistakenly attacks hair follicles, leading to hair loss. This autoimmune response can result in patchy hair loss or more widespread thinning, and it is often seen in conditions like alopecia areata.

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  43 upvotes   4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes   2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

      community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

      in Minoxidil  38 upvotes   1 year ago
      The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

      community Fin/dut increase in estrogen and autoimmune diseases

      in Chat  6 upvotes   1 year ago
      The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community dutasteride 9 months, nonstop hair loss

      in Finasteride/Dutasteride  31 upvotes   2 years ago
      Experiencing continual nonstop hair loss despite using dutasteride for 9 months, and the possible causes behind it being discussed such as nutritional deficiencies, elevated cortisol, vitamin D deficiency or other problems. Other solutions such as minoxidil and finasteride have been suggested.

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  19 upvotes   11 months ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.

      community The ultimate regiment to reverse hairloss

      in Treatment  6 upvotes   1 year ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community Autoimmune issue?

      in Question  2 upvotes   6 years ago
      The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes   2 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

      community Take A Vitamin D Blood Test!!!

      in Treatment  48 upvotes   2 years ago
      Low Vitamin D can cause hair shedding, and taking 5000 IU of Vitamin D daily reduced shedding significantly. Vitamin D deficiency is common and correcting it can benefit overall health.

      community Ruxolitinib - Start of a case study

      in Research/Science  12 upvotes   2 months ago
      The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

      community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

      in Chat  15 upvotes   4 months ago
      A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.

      community Medications that cause extra hair growth

      in Research/Science  119 upvotes   10 months ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community Dutasteride broked my liver (maybe)

      in Finasteride/Dutasteride  8 upvotes   1 year ago
      A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  736 upvotes   1 year ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes   2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community 14 yrs Fighting the Good Fight - A Summary

      in Treatment  40 upvotes   3 years ago
      A user shared their 14-year experience with hair loss treatments, primarily using finasteride, minoxidil, and Nizoral. They highlighted the effectiveness of finasteride despite some side effects and emphasized the importance of early prevention and the potential for negative selection bias in online reviews.

      community Finally Shaved It

      in Shaved/buzzed  102 upvotes   4 years ago
      User tired of receding hairline and maintenance, shaved head. Others compliment shaved look and beard genetics.

      community 15 years old bad hair loss! I need tips

      in Update  8 upvotes   5 years ago
      Hair loss since age 13 due to scalp disease with dandruff, flaking, and itching. Seeking advice on using Minoxidil for regrowth and other tips.

      community Xeljanz....the magic drug!!!

       2 upvotes   6 years ago
      A user experienced significant hair regrowth from Xeljanz after severe alopecia but can no longer afford it. They are seeking ways to obtain the medication despite its high cost and potential side effects.

      community 50% test increase after 18 months of taking DUT

      in Update  57 upvotes   2 weeks ago
      A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.