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GlossarySusceptibility Loci

specific gene locations linked to higher disease risk

Susceptibility loci are specific locations on genes that are associated with an increased risk of developing certain diseases or conditions, such as alopecia. These genetic markers can help identify individuals who are more likely to experience these health issues, providing valuable information for both diagnosis and potential treatment strategies.

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community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 1 year ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community NBC News: Finasteride is increasingly being prescribed even before baldness begins

in Finasteride/Dutasteride 360 upvotes 5 months ago

Finasteride is increasingly prescribed to young men to prevent hair loss, with many users expressing regret for not starting sooner. The conversation highlights the preference for Finasteride, Dutasteride, and Minoxidil over other treatments.

community For what it's worth, I just want to state that I also think that adding Dutasteride to Finasteride has made my hair worse

in Finasteride/Dutasteride 18 upvotes 3 years ago

A user shared that adding Dutasteride to Finasteride worsened their hair loss, despite initial improvements with Finasteride alone. Others in the conversation debated the effectiveness of Dutasteride, with some suggesting individual responses vary and others defending its proven efficacy for hair loss.

community Still not sure why men think diet has nothing to do with hair loss when scientific is quite the opposite [Link]

25 upvotes 6 years ago

Diet can influence hair health, but male pattern baldness (MPB) is primarily genetic. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 1 year ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 month ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 month ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Let's be clear, does Finasteride stop MPB as long as it's taken?

in Finasteride/Dutasteride 170 upvotes 7 months ago

Finasteride is believed to slow down hair loss significantly, but may not completely stop it for everyone. Effectiveness and duration vary by individual, with some users experiencing positive results for over 10 years, while others see less benefit.

community Low level chronic allergies and hair loss

in Research/Science 6 upvotes 10 months ago

Hair loss can be influenced by chronic low-level allergies, and treatments like fexofenadine or topical cetirizine may help with regrowth. The user avoids finasteride, dutasteride, and minoxidil, and has tried Regenera Activa and PRF sessions.

community Why does finasteride stop working?

in Finasteride/Dutasteride 26 upvotes 1 month ago

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

community 1 month of using fin, so happy

in Progress Pictures 863 upvotes 3 months ago

User had a hair transplant and used a finasteride and minoxidil spray for 6 months with no results. After adding finasteride tablets for 1 month, they saw significant hair growth improvement.

community Do you believe there will be a game changing treatment in the next 10 years?

in Chat 67 upvotes 2 years ago

Users discuss potential game-changing hair loss treatments in the next 10 years. Some mention KX-826, SCUBE3, and stem cells as promising options, while others express doubt due to past disappointments and lack of focused research.

community Hey /r/ Tressless, thought it would be interesting to take a full journey of hair restoration with you! DAY 1825

in Finasteride/Dutasteride 18 upvotes 4 years ago

The efficacy of various hair loss treatments, including Finasteride and Dutasteride, with personal anecdotal evidence about potential side effects. It also includes advice to get a male hormone blood panel done before starting treatment, and lifestyle changes to minimize side effects.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 1 year ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community Is Fagron TrichoTest (first genetic test for hair loss) a SCAM?

in Research/Science 8 upvotes 1 year ago

User ronopibf discusses Fagron TrichoTest, a genetic test for hair loss, and seeks opinions on its effectiveness. Some users support the service, while others call it a scam, with prices ranging from $200-$500.

community My hair journey as a 20+ year old with genetic hair loss and thoughts of pregnancy soon

in Female 1 upvotes 1 month ago

A 28-year-old woman with genetic hair loss has tried various treatments, including oral minoxidil, finasteride, dutasteride, vitamins, ketoconazole shampoo, exosome needling, and hair extensions. She plans to pause treatments for pregnancy and is concerned about potential hair loss during that time.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 8 months ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 17 upvotes 1 month ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community The closest thing to a cure before hair cloning or genetic via?

in Treatment 9 upvotes 1 year ago

The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hair growth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Do we know exactly why some people respond so great to dut/fin,min and others dont?

in Research/Science 29 upvotes 1 week ago

Genetic factors, enzyme activity, and DHT sensitivity affect individual responses to hair loss treatments like finasteride, minoxidil, and dutasteride. Starting treatments early can slow hair loss, but results vary among individuals.

community Vegan Protein Powder Make Loss Worse?

in Female 2 upvotes 3 months ago

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

community Welcome to Tressless, OG! Ötzi was dark-skinned and balding.

in Chat 11 upvotes 1 year ago

The conversation discusses that genetic analysis of the Iceman Ötzi shows he had male-pattern baldness and dark skin, with a joke about using beards and tattoos to distract from hair loss. No specific hair loss treatments are mentioned.

community How does hair loss and recovery work?

in Chat 12 upvotes 2 months ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community 29f Female on Dutasteride Progress.

in Female 14 upvotes 1 year ago

A 29-year-old woman with genetic hair loss started using 0.5 dutasteride a week ago and has noticed increased shedding, no sexual side effects, and less oily skin. She plans to provide updates and is not concerned about potential birth defects as she doesn't plan to have more children.

community Do I need to get professional advice?

in Advice 6 upvotes 5 years ago

A 22-year-old woman is experiencing genetic hair loss and has tried natural remedies like coconut oil and aloe vera without success. She seeks advice on whether to see a dermatologist or use treatments like Minoxidil (Rogaine) despite her parents' skepticism about professional help and chemical treatments.

community Hair growth and natural remedies? Are they worth of it ..

in Treatment 1 upvotes 4 months ago

The user discusses using Minoxidil and plans to start Finasteride for genetic hair loss. They also mention natural remedies like gold shilajit, moringa powder, a seed mixture, and cardio exercise, emphasizing that while these can help, Minoxidil and Finasteride are necessary.

community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

in Chat 17 upvotes 1 year ago

The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

community Is there any way to know for sure if hair thinning is just from fungal infection/ inflammation and would be reversed with just Ketoconazole 2%/ triamcinolone acetonide etc?

2 upvotes 9 years ago

The user is unsure if their hair thinning is due to fungal infection/inflammation or genetic factors and is hesitant to start Minoxidil, finasteride, and RU58841. They are currently using Ketoconazole 2% and triamcinolone acetonide and are concerned about potential side effects from other medications.