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GlossaryG-protein coupled receptor

cell surface receptor that transmits external signals inside cells

A G-protein coupled receptor (GPCR) is a type of cell surface receptor that plays a crucial role in transmitting signals from outside the cell to the inside. When a molecule, such as a hormone or neurotransmitter, binds to a GPCR, it activates an associated G-protein, which then triggers various cellular responses. This mechanism is essential for many physiological processes, including sensory perception, immune response, and cell communication.

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community What other factors than DHT causes hair loss – and what to do about it?

in Treatment 2 years ago

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 11 months ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 51 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Roughly 1.5 years progress. Dut, Fin, Minox, RU.

in Progress Pictures 802 upvotes 2 years ago

A user's progress with treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, and RU. Other members of the conversation provided tips such as using Microneedling and Tretinoin to increase regrowth and wounding areas of the scalp that are thinning in order to fill them in.

community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders

in Research/Science 42 upvotes 2 months ago

Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.

community 26, i was cool w shaving bald but I wanted to hold on for a little longer. Just topical min and rosemary shampoo.

in Progress Pictures 688 upvotes 1 year ago

The post and conversation are about a user's successful regrowth of hair using topical minoxidil and rosemary shampoo. Other users discuss the potential limitations of minoxidil and recommend using finasteride to maintain hair growth.

community I have a hard time believing that creatine overpowers fin/dut

in Finasteride/Dutasteride 111 upvotes 1 year ago

The conversation is about whether creatine causes hair loss in individuals who are taking finasteride or dutasteride for hair loss. Some users report experiencing hair loss when taking creatine, while others do not. There is no consensus on the issue.

community It’s over. NOTHING has worked.

in Chat 95 upvotes 1 year ago

A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 1 year ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Boys how is no one seeing positive results from pyrilutamide

in Chat 27 upvotes 1 year ago

Pyrilutimide, a treatment for hair loss; it's effectiveness compared to other treatments such as Finasteride and RU58841; and some users’ experiences with the treatment.

community Quit vaping/smoking = 80% less loss

in Research/Science 214 upvotes 4 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community 5 Months Results – Fin/Min/Keto Shampoo/Dermapen

in Progress Pictures 720 upvotes 1 year ago

Treatments for hair loss, including using finasteride and minoxidil regularly, together with keto shampoo and dermapen; the user's progress since starting treatment five months ago; and discussion of potential side effects.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 77 upvotes 8 months ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community 1 1/2 Year Results on Finasteride

in Finasteride 188 upvotes 5 years ago

A user sharing their positive experience with taking finasteride as part of their hair loss treatment regimen, which also included biotin, Nizoral Shampoo, OGX Biotin & Collagen Shampoo, and iRestore Laser Cap. Others shared their own experiences and advice on treating hair loss.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 233 upvotes 3 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

community Topical fin and min and swallowing semen

in Finasteride/Dutasteride 118 upvotes 2 months ago

A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

community Another Creatine + Finasteride Experiment With Bloodwork

in Update 282 upvotes 2 years ago

Experimenting with the effects of creatine and finasteride on DHT levels, as well as a discussion regarding the potential link between creatine supplementation and hair loss.

community Fuck hair loss; acquire beard.

in Shaved/buzzed 933 upvotes 2 years ago

A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

community Best hair loss treatments ranked: a complete guide

361 upvotes 5 years ago

Hair loss treatments, including Dutasteride 0.5mg daily, finasteride 1mg daily, minoxidil 5% 2x daily, dermarolling, low-level light therapy (LLLT), ketokonazole shampoo, and diet optimization; discussing their effectiveness and side effects.

community Personal results (1mg finasteride + 10.000mcg biotine) after almost 3 years. Not as impressive as some here, but maybe provides a more realistic view.

in Progress Pictures 479 upvotes 2 years ago

Jericho1017 shared their hair regrowth results after nearly 3 years using 1mg finasteride and 10,000mcg biotin daily, with noticeable improvement after 1.5 years and no significant side effects except for watery semen. Some users suggested adding minoxidil and microneedling to improve results, but Jericho1017 is currently content with their progress and not looking to add more treatments.

community The most depressing things about hair loss for me

in Chat 24 upvotes 3 years ago

The emotional impact of hair loss and the risks associated with common treatments such as finasteride, dutasteride, minoxidil, RU58841, and Fluridil. People discussed their personal experiences with these treatments, including potential side effects and lowered fertility. Hair transplants were also mentioned as a possible solution.

community Fats on your Head to Stop Hair Loss?

in Research/Science 140 upvotes 6 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 111 upvotes 11 months ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community started RU58841 today and am panicing

in Treatment 8 upvotes 1 year ago

A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

community [M30] 15 months FIN + nizoral progress

in Finasteride/Dutasteride 528 upvotes 1 year ago

User experienced significant hair regrowth using 1.25mg Finasteride daily and Nizoral once a week for 15 months. Noticeable results appeared after 6 months, with no side effects reported.

community Minox and fin since start of January 2020, also shaved my head twice since then to get full effects of the minoxidil and reach the whole scalp easier, that’s honestly a huge key

in Progress Pictures 234 upvotes 3 years ago

User experienced significant hair regrowth using Minoxidil and Finasteride since January 2020, with no side effects reported. Shaving head twice helped Minoxidil reach scalp more effectively.

community 90 days. Did not think this was possible before finding this subreddit. To say I’m obsessed is an understatement. Excuse my poor photo stitch.

in Progress Pictures 333 upvotes 1 year ago

User experienced significant hair regrowth after 90 days using Dutasteride, oral and topical Minoxidil, RU58841, dermarolling, and Keto shampoo. Others discuss potential side effects and difficulty determining which treatment is most effective.

community I started rapidly diffuse thinning at 22. I’m 42 now and have as much hair as I did at 16. AMA

in Treatment 450 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.