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    GlossaryBulge Cells

    specialized stem cells in hair follicles aiding growth and repair

    Bulge cells are specialized stem cells located in the hair follicle's bulge area, which is a region near the base of the hair follicle. These cells play a crucial role in hair growth and regeneration, as they have the ability to differentiate into various cell types needed for the hair follicle's structure and function. For professionals, it's important to note that bulge cells are also involved in wound healing and can contribute to the regeneration of the epidermis.

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      community Redensyl Megathread !!!!

       44 upvotes 4 years ago
      Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

      community Best Microneedle Lengths To Stimulate Stem Cells

      in Microneedling  18 upvotes 1 year ago
      Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

      community Clearing the air on how non-surgical treatments really work

       18 upvotes 5 years ago
      Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Hair theory Scar tissue and Verteporfin

      in Chat  25 upvotes 5 months ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  40 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

      in Progress Pictures  31 upvotes 11 months ago
      A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  194 upvotes 1 month ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community microneedle, any long term users damage?

      in Microneedling  35 upvotes 5 months ago
      Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

      community 6 month hairline results (dutasteride and microneedling)

      in Progress Pictures  799 upvotes 4 years ago
      A user's 6 month hairline results from using dutasteride and microneedling, which resulted in successful regrowth of their thinning temples. Other users commented with similar experiences that were also achieved through the use of finasteride, dutasteride and minoxidil.

      community Progress so far after a little over a year (23M)

      in Progress Pictures  2741 upvotes 5 months ago
      A 23-year-old shared his hair regrowth progress after using Minoxidil, finasteride, Dutasteride, and RU58841 for over a year. The post received supportive comments, with others sharing their own experiences and complimenting his transformation.

      community A Nuanced Look at Microdosing Topical Finasteride

      in Finasteride/Dutasteride  85 upvotes 11 months ago
      The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

      community RU58841 alone vs. with Fin / Dut

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.

      community Dutasteride Mesotherapy Works – Just 1 month results

      in Progress Pictures  109 upvotes 2 years ago
      The effectiveness of using dutasteride mesotherapy as a hair loss treatment, with other protocols such as microneedling, vitamin D and B12, zinc, and biotin. The user's results were positive after 4-6 months without any serious side effects.

      community Where do you guys buy your stuff?

      in Product  8 upvotes 5 months ago
      The post discusses purchasing hair loss treatments like oral minoxidil and finasteride, which were found cheaply in Argentina. The user asks where others buy similar products, including topical minoxidil, finasteride, dutasteride, and RU58841.

      community Any other celebrities known to be taking finasteride ?

      in Finasteride/Dutasteride  455 upvotes 6 months ago
      The conversation discusses various celebrities who reportedly use hair loss treatments like finasteride and dutasteride. Users share their experiences and opinions on starting treatment, with some encouraging the original poster to consult a dermatologist and consider treatment before it's too late.

      community Does anyone here use everything except Fin

      in Minoxidil  23 upvotes 1 year ago
      The conversation is about hair loss treatments, specifically Minoxidil (Min) and Finasteride (Fin). The original poster is considering using Min and other treatments but is hesitant about Fin, while the responses vary, with some advocating for early use of Fin and others warning about potential side effects.

      community Have I progressed or is it just my imagination?

      in Is this regrowth?  279 upvotes 1 year ago
      The conversation is about someone noticing hair regrowth after using a scalp massager and considering a hair transplant. People suggest using finasteride or dutasteride, but there's debate on their effectiveness and side effects. Some see progress, while others are skeptical without consistent photo evidence.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 3 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.