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GlossaryCyclosporine

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment

research A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment

24 citations, May 2010 in “Veterinary dermatology”

Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.

Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

21 citations, April 2010 in “Veterinary Dermatology”

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

research Successful Treatment of Sebaceous Adenitis in a Rabbit with Ciclosporin and Triglycerides

13 citations, December 2008 in “Veterinary dermatology”

A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.

research Simvastatin-Induced Myoglobinuric Acute Kidney Injury Following Ciclosporin Treatment for Alopecia Universalis

3 citations, February 2010 in “Clinical kidney journal”

Combining ciclosporin and simvastatin can cause severe kidney damage.

research Clinical And Histological Recovery Of Non-Thymoma-Associated Exfoliative Dermatitis In A Cat Treated With Ciclosporin A

1 citations, January 2020 in “Journal of Feline Medicine and Surgery Open Reports”

Ciclosporin A effectively treated a cat's severe skin condition.

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community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 2 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community The DEFINITIVE cure for hairloss

in Satire 270 upvotes 2 weeks ago

The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 1 month ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 3 months ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

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