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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  641 upvotes 4 months ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

      community Could Finasteride theoretically induce chronic telogen effluvium?

      in Finasteride/Dutasteride  7 upvotes 6 months ago
      A user experienced continuous hair shedding for 13 months after starting finasteride, suspecting it might cause chronic telogen effluvium, and considered switching to dutasteride or stopping medication. Other users suggested that finasteride doesn't cause hair loss, recommending dutasteride for more aggressive hair loss, while some advised against stopping medication.