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Did you mean Chemokine Receptor?

Glossary Chemokine Receptor

protein on cell surface that binds signaling molecules called chemokines

A chemokine receptor is a type of protein found on the surface of certain cells that binds to chemokines, which are signaling molecules. This interaction helps direct the movement of immune cells to sites of inflammation, infection, or injury. Chemokine receptors play a crucial role in the immune response and are also involved in various diseases, including cancer and autoimmune disorders.

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research Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin

286 citations , June 2012 in “Nature Immunology”

In this study, researchers found that mouse hair follicles recruit Langerhans cells by secreting chemokines, acting as key portals for these cells in both mice and humans.

research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium

181 citations , January 2019 in “Cell”

In this research, authors found that skin-resident ILCs regulate sebaceous gland function and microbial balance, emphasizing an immune-epithelia system that supports host-microbe symbiosis.

research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin

192 citations , March 2017 in “Cell host & microbe”

The researchers reported that hair follicle development and commensal microbe colonization promote the accumulation of regulatory T cells in neonatal skin, with the Ccl20-Ccr6 pathway playing a key role in this process.

research Author response: IL18 signaling promotes homing of mature Tregs into the thymus

July 2020

This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.

research Stress-induced chemokine production by hair follicles recruits dendritic cells to sites of minor trauma

December 2012 in “Journal of dermatological science”

This study reveals that hair follicles in mice and humans recruit epidermal Langerhans cells during skin inflammation via specific chemokine signaling pathways.

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