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    Did you mean Candidate Genes?
    Glossary Candidate Genes

    specific genes believed to influence a particular trait or disease

    Candidate genes are specific genes that researchers believe may be associated with a particular trait or disease, based on their known biological functions or previous studies. For example, in the context of alopecia (hair loss), scientists might identify candidate genes that are involved in hair growth or immune system regulation, as these processes are relevant to the condition. Identifying and studying these genes can help in understanding the underlying mechanisms of the disease and potentially lead to targeted treatments.

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    1. A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits Genetics selection evolution · 2021 · 11 citations
    2. sc-eQTL unveil Immunogenetic Architecture of Polycystic Ovary Syndrome 2025
    3. MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 2 citations
    4. sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome Scientific Reports · 2026
    5. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    6. Large-Scale Plasma Proteomics and Genetic Integration Uncover Novel Biological Pathways in Male Pattern Baldness International Journal of Molecular Sciences · 2026
    7. A mechanism-informed deep neural network enables prioritization of regulators that drive cell state transitions Nature Communications · 2025 · 13 citations
    8. LB1053 Dysregulation of antioxidant enzyme PRDX5 in alopecia areata Journal of Investigative Dermatology · 2019 · 1 citations
    9. Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters BMC Genomics · 2018 · 16 citations
    10. The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study Journal of Investigative Dermatology · 2017 · 15 citations
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