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research Exploring the “brain-skin connection”: Leads and lessons from the hair follicle

30 citations , October 2016 in “Current research in translational medicine”

This essay reviews the role of human scalp hair follicles in the "brain-skin connection," highlighting their dual function as targets and sources of neurohormones, without reporting new experimental results.

research 51012 Clinical and pathophysiological study of seborrheic capitis: focus on brain-skin connection

September 2024 in “Journal of the American Academy of Dermatology”

Seborrheic dermatitis affects quality of life and sleep, linked to stress and nervous system changes.

research Brain–skin connection: The contemporary perspective through neuroendocrinology

January 2020 in “Turkish Journal of Dermatology”

This review discusses the role of the CRH–ACTH–cortisol axis in skin function and its potential link to stress-related skin and hair conditions, and reports no new experimental results.

research Neuroimmunoendocrine circuitry of the ‘brain-skin connection’

293 citations , November 2005 in “Trends in Immunology”

This study indicates that stress in mice recruits specific neuroimmunoendocrine elements, leading to neurogenic skin inflammation that inhibits hair growth and highlights the skin's role in stress response research.

research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.

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Community Join

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community How to treat skin when using minoxidil?

6 upvotes 6 years ago

Minoxidil may cause skin issues like wrinkles and dark undereyes, possibly due to alcohol content. Alternatives include collagen supplements, vitamin C, and skincare products; some users prefer finasteride for hair loss without these side effects.

community Study: You can safely conceive on Dutasteride

in Research/Science 95 upvotes 1 year ago

Dutasteride is considered safe for conception, with semen concentrations being too low to cause harm. Users discuss switching between dutasteride and finasteride, with some experiencing side effects like acne and heart issues, and advice is given to maintain a consistent treatment regimen.

community Do you believe these studies are real or just fear mongering

in Finasteride/Dutasteride 157 upvotes 11 months ago

Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.

community Intermittent Finasteride dosing for reduction of side effects?

6 upvotes 7 years ago

Intermittent finasteride dosing, like taking it every third day, may reduce side effects while still lowering DHT levels. Users report side effects such as brain fog and weaker erections, which often subside after stopping the drug.

community Blaming Finasteride doesn't help you solve anything: dry eyes

51 upvotes 1 year ago

Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

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Learn

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learn Neem Oil

Oil from the neem tree, used in traditional remedies

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Clinics

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Hair Loss Treatments
Braun Dermatology & Skin Cancer CenterAlexandria, VA · US

Experts

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SMP Specialist
Noelle Skin
Nice, France

Noelle Skin