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5 / 10 resultslearn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
learn Baricitinib
JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases
learn Metformin
diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
Research
5 / 1000+ resultsresearch Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders
This study analyzed gene expression in 2 canines with Vogt-Koyanagi-Harada syndrome (VKH) and 1 with vitiligo to explore the immunopathogenesis of these autoimmune pigmentary disorders. The research found that T cell gene signatures, including IFNG, TNF, PRF1, IL15, CTSW, CXCL10, and CCL5, were upregulated in affected dogs compared to healthy controls, mirroring findings in humans. Additionally, genes such as FOXP3 and TBX21 were enriched, while IGFBP5, FOXO1, and PECAM1 were decreased. The study also identified TGFB3, SFRP2, and CXCL7 as potential contributors to these disorders. These findings suggested that the immunopathogenesis of VKH and vitiligo is conserved between dogs and humans, providing insights that could aid in developing targeted therapies and predicting treatment responses.
research Gender Aspects in Skin Diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
research Contents
The document concludes that there have been significant advances in the treatment and diagnosis of various skin conditions.
research Melanin Pigmentary Disorders: Treatment Update
Treatments for melanin disorders exist, but more effective options needed.
research Phototherapy, Photomedicine, and Pigmentary Disorders
Stopping certain drugs can improve skin conditions, arsenicosis affects over half of a Bangladeshi village, males are more vulnerable, and certain treatments are effective for warts, acne, and psoriasis. Smoking and drinking are linked to psoriasis in men, a cream helps with a type of skin cancer, and low iron levels don't directly cause chronic hair loss in women.
Community Join
5 / 255 resultscommunity Autoimmune disease and balding
A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.
community Autoimmune issue?
The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.
community Fin/dut increase in estrogen and autoimmune diseases
The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.
community Lilly to seek first approval of an autoimmune drug for hair loss
Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.
community The Worst Hair Loss Condition You (MAY) have: LPP
Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.