research The effect of the antiandrogen IIα-hydroxyprogesterone on sebum production and cholesterol concentration of sebum
The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.
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research The Effect of Anti-Androgens on the Response of Rat Preputial Glands to Testosterone*
This study reports that new compounds with anti-androgenic effects were found to counteract testosterone in animals without significant estrogenic activity, indicating potential for managing androgen-related conditions.
research Therapeutic effect of finasteride through its antiandrogenic and antioxidant role in a propionic acid-induced autism model: Demonstrated by behavioral tests, histological findings and MR spectroscopy
In this animal study, finasteride significantly improved autism-like symptoms in rats by reversing biochemical markers and enhancing behaviors, potentially due to its antioxidant and anti-androgen effects.
research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position
This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
research The Effect of Mesenchymal Stem Cells Derived-Conditioned Media in Combination with Oral Anti-Androgenic Drugs on Male Pattern Baldness: An Animal Study.
In this study using animal models, umbilical cord stem cell conditioned media combined with oral anti-androgens improved hair regeneration in androgenetic alopecia, enhancing hair follicle cycles and reducing inflammation, suggesting potential as a promising therapy.
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5 / 666 resultscommunity If RU58841 is such an effective anti androgen
RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.
community I Get Side-Effects from Anti-Androgens
Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.
community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?
RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.
community Topical Anti Androgens detailed thread
Users discuss the effectiveness of topical anti-androgens like RU58841, Pyri (KX826), and CB for hair loss. Some report maintenance and regrowth with Pyri, while others find limited success with RU58841 and switch to combinations like finasteride and minoxidil or minoxidil and dutasteride.
community I want to add a topical anti androgen to my routine
RU58841 is considered an effective topical anti-androgen for hair loss, often used with minoxidil. Concerns exist about its purity and sourcing since it's not FDA-approved.
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6 / 12 results- Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide may be a safer topical alternative to oral antiandrogens like finasteride.
- What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.
learn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn Bicalutamide
a nonsteroidal anti-androgen, most commonly used orally for women
learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
learn Fluridil
a topical anti-androgen with less systemic involvement
learn GT20029
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