April 2024 in “Current Rheumatology Reviews” Mixed Connective Tissue Disease (MCTD) in children is rare and often presents with overlapping features of multiple rheumatologic disorders. This report discusses an 8-year-old girl with symptoms including fever, hair loss, lower extremities edema, weakness, and oral ulcers, who was diagnosed with MCTD due to a high titer of anti-U1 RNP antibodies. Treatment with immunomodulator drugs led to disease remission. The case highlights the diagnostic challenges of MCTD in pediatric patients and suggests that serum anti-U1 RNP testing can be a valuable diagnostic tool, especially in cases with recurrent muscular weakness, lupus-like symptoms, and edema.
June 2023 in “Romanian Medical Journal” The case shows how hard it is to tell apart Multiple Autoimmune Syndrome from other similar autoimmune conditions, but correct diagnosis is key for treatment to work.
Different connective tissue disorders have unique symptoms and treatments, with varying outcomes and often require ongoing care from a specialist.
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August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.