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research Interest of an anti-hair loss serum containing Silybum marianum extract, manganese pyrrolidone carboxylic acid (PCA), and a Lespedeza capitata extract in the management of post-cancer treatment alopecia: an international real-world study

January 2026 in “EJC Skin Cancer”

This research underscores the significant challenge of managing hair loss after cancer treatment and explores the need to evaluate new topical strategies to promote faster and higher-quality hair regrowth, as existing recovery processes are often slow and sometimes incomplete.

research Anti-androgen therapy for the treatment of female pattern hair loss: a clinical review of current and emerging therapies

May 2025 in “Journal of the American Academy of Dermatology”

This review highlights the available and investigational anti-androgen treatments for female pattern hair loss in the US, noting their limitations and the potential for fewer systemic side effects with topical options compared to oral medications.

research An anti‐hair loss treatment in the management of mild androgenetic alopecia: results from a large, international observational study

1 citations , September 2021 in “Dermatologic Therapy”

In this observational study, AC5 reduced hair loss in 89% of subjects with mild androgenic alopecia, and was well tolerated and appreciated by most participants.

research Hair Loss Treatment Shows Anti-inflammatory Activity in vitro

1 citations , January 2012 in “Hair therapy & transplantation”

This review discusses hair loss treatments with natural compounds, noting their good safety profile but highlighting insufficient peer-reviewed data to support their effectiveness.

research Interest of an anti–hair loss shampoo supplement used alone and in association with the reference treatment in the management of hair loss

August 2019 in “Journal of the American Academy of Dermatology”

The shampoo helps reduce hair loss and improves Minoxidil® absorption.

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Community Join

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community Is it worth using anti-hair loss shampoo?

in Product 2 upvotes 7 months ago

Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

community Anti-oxidants that reverse hairloss?

86 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community 2-Month Progress on Hair Loss Treatment: Is It Working ?

7 upvotes 4 months ago

The user is using Minoxidil, Finasteride, a dermaroller, vitamin D, and anti-hair loss shampoo for hair loss treatment. There is some vellus regrowth, and shedding may indicate future terminal hair growth.

community Is Pyrilutamide still a thing as anti-androgen and hair loss ?

in Product 3 upvotes 2 years ago

The user tried topical dutasteride for 6 months without success and is considering Pyrilutamide as an anti-androgen treatment for hair loss. Other users suggest using 1% Pyrilutamide and combining it with topical dutasteride.

community Hair loss progress update, 10 months on new protocol

4 upvotes 3 months ago

The user updated their hair loss treatment by increasing topical finasteride, adding topical anti-androgens, vitamin D, biotin, and scalp massages, while considering switching from 2% to 5% minoxidil for better results. Feedback suggests progress is stable, and increasing minoxidil may improve hair density.

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Learn

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learn HMI-115

HMI-115: Frequently Asked Questions About Hair Loss Treatment HMI-115 is an investigational anti-prolactin-receptor antibody being trialled for androgenetic alopecia. It is not approved anywhere; its hair-loss evidence is a 16-person Phase 1b announced only by press release, plus a completed 192-man Phase 2 in China whose results are not yet published.

learn Azelaic Acid

Is azelaic acid a treatment on its own or does it need supplements? One small randomised trial (26 women) found 5% azelaic acid comparable to 2% minoxidil in female pattern hair loss, and the anti-DHT rationale otherwise rests on in-vitro work — community members generally describe azelaic acid as an add-on to minoxidil or finasteride rather than a standalone treatment.

learn Cetirizine

popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Fluridil

a topical anti-androgen with less systemic involvement

learn Aminexil

Aminexil: Can I combine it with anti-hair loss shampoos or will it lose effectiveness? You can safely combine Aminexil with anti-hair loss shampoos for enhanced effectiveness.

learn GT20029

What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

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Clinics

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All 77 clinic results →

Experts

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