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research Evaluation of hair growth-promoting, anti-inflammatory, and 5α-reductase inhibitory effects of Spirulina extract using in vitro and in vivo models

July 2025 in “Biotechnology and Bioprocess Engineering”

Spirulina extract may effectively promote hair growth and reduce inflammation, offering a natural alternative for hair loss treatment.

research Gynostemma pentaphyllum Makino extract induces hair growth and exhibits an anti‐graying effect via multiple mechanisms

4 citations , August 2023 in “Journal of Cosmetic Dermatology”

Gynostemma pentaphyllum extract may help grow hair and prevent graying.

research Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B

72 citations , January 2012 in “Annals of Dermatology”

In this study, IGF-I was shown to enhance human hair follicle growth, maintain the anagen phase, and increase expression of certain growth factors and anti-apoptotic markers.

research Anti-oxidant Efficacy and Effects on Expression of Growth Factors in Human Hair Follicle Dermal Papilla Cells of Rosa multiflora Root Extracts

6 citations , June 2017 in “Asian journal of beauty & cosmetology”

In this study, Rosa multiflora root extracts showed strong antioxidant activity and promoted expression of growth factors IGF1 and PDGFB, suggesting potential use as a natural hair growth agent.

research Faculty Opinions recommendation of Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B.

January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

IGF-I helps hair growth by preventing cell death and boosting growth factors.

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Community Join

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community ND dropped ecklonia cava which can cause hair growth. Alternative to fin/dut for those who have side effects

6 upvotes 1 year ago

Ecklonia cava is suggested as an alternative to finasteride and dutasteride for hair growth, potentially offering benefits without their side effects. It is promoted for anti-aging, mood enhancement, and cognitive support.

community Has anyone tried AutumnValley Anti-hair Loss Complex Pack before?

in Chat 1 year ago

The conversation discusses the effectiveness of the AutumnValley Anti-hair Loss Complex Pack for hair growth and hair loss prevention. The original poster is considering adding it to their regimen, which already includes Minoxidil, finasteride, and RU58841.

community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 10 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community Anti-oxidants that reverse hairloss?

86 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Bicalutamide and muscles growth

7 upvotes 1 year ago

A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

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Learn

7 / 14 results

learn Valproic acid

Anti-seizure and mood-stabilising drug

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Cetirizine

Antihistamine allergy medicine

learn Ketoconazole

Antifungal, best known as a dandruff shampoo

learn Piroctone Olamine

How does piroctone olamine fight dandruff, and does it affect hair growth? Piroctone olamine is an antifungal used in anti-dandruff shampoos. In one 2002 trial it reduced dandruff and shedding, but hair density did not change.
Can Piroctone Olamine be combined with hair growth treatments like Minoxidil? There is no known interaction, but the combination has not been studied. Many people use an anti-dandruff shampoo alongside minoxidil; ask a pharmacist if your scalp is irritated.

learn Exosomes

What does Fluridil do on the scalp, and how does it block the DHT hormone? Fluridil is a topical anti-androgen sold in some European countries. One small 2002 trial led by its developer reported more hairs in the growth phase; it is not FDA-approved and the evidence is limited.

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Clinics

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Experts

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Dermatologist
Andi Iryanti, M. Biomed
Indonesia

Andi Iryanti, M. Biomed