Search
for

    Did you mean Hypohidrotic Ectodermal Dysplasia?
    Glossary Hypohidrotic Ectodermal Dysplasia

    genetic disorder causing sparse hair, missing teeth, and reduced sweating

    Hypohidrotic Ectodermal Dysplasia (HED) is a genetic disorder that affects the development of the skin, hair, nails, teeth, and sweat glands. Individuals with HED often have sparse hair, missing or malformed teeth, and an inability to sweat properly, which can lead to overheating. This condition is also known as anhidrotic ectodermal dysplasia or Christ-Siemens-Touraine syndrome.

    Related Terms

    Research 10 of 159

    1. Anhidrotic Ectodermal Dysplasia: Predisposition to Bronchial Disease Annals of Internal Medicine · 1971 · 32 citations
    2. Genotype-phenotype correlation in boys with X-linked hypohidrotic ectodermal dysplasia American Journal of Medical Genetics · 2014 · 35 citations
    3. Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation Developmental Dynamics · 2015 · 15 citations
    4. Store-operated calcium channels in skin Frontiers in Physiology · 2022 · 6 citations
    5. Scleromyxedema with neurologic involvement: Therapy with intravenous immunoglobulin Journal of the American Academy of Dermatology · 2010
    6. Mutational spectrum in 101 patients with hypohidrotic ectodermal dysplasia and breakpoint mapping in independent cases of rare genomic rearrangements Journal of Human Genetics · 2016 · 30 citations
    7. Molecular basis of hypohidrotic ectodermal dysplasia: an update Journal of Applied Genetics · 2015 · 85 citations
    8. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    9. Advances in the genetic understanding of hypohidrotic ectodermal dysplasia Expert opinion on orphan drugs · 2017 · 1 citations
    10. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →