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research The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms

1 citations , July 2022 in “JEADV Clinical Practice”

This abstract outlines a guide reviewing both FDA-approved and off-label therapies for androgenetic alopecia and proposes treatment algorithms based on scientific research, highlighting a gap in common treatments for this prevalent condition.

research Topical dutasteride for androgenic alopecia: current state and prospects

December 2024 in “Therapeutic Delivery”

This review discusses the current therapies for androgenic alopecia, emphasizing topical formulations like minoxidil and finasteride and exploring the potential of dutasteride-loaded nanocarriers for targeting hair follicles to minimize systemic side effects from oral treatment.

research PARIETAL AND OCCIPITAL HAIR LOSS PATTERNS IN INITIAL STAGES OF ANDROGENIC ALOPECIA IN MEN

May 2023 in “Vestnik dermatologii i venerologii”

In this study, researchers examined men with early-stage androgenetic alopecia and found distinct patterns of hair loss correlated with genetic and hormonal factors, noting that parietal region pattern hair loss responded better to minoxidil and micronutrient treatment compared to occipital region pattern.

research Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride

24 citations , January 2006 in “Skin Pharmacology and Physiology”

This study found that finasteride (1 mg/day) appeared to reverse the shortening of the hair cycle in androgen sensitive sites but did not convert miniaturized hair into terminal hair.

research THE FIBROBLAST AS A MODEL FOR ANDROGEN RESISTANT STATES

29 citations , May 1988 in “Clinical Endocrinology”

Fibroblasts help understand androgen resistance at the cellular level.

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Community Join

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community I need advice on my status quo, further actions and diagnostic

in General 163 upvotes 1 year ago

The user is experiencing hair loss, possibly due to androgenic alopecia or telogen effluvium, and is considering treatments like Minoxidil, Finasteride, or RU58841. They also mention potential iron deficiency and sleep deprivation as contributing factors.

community Topical Anti Androgens detailed thread

6 upvotes 2 months ago

Users discuss the effectiveness of topical anti-androgens like RU58841, Pyri (KX826), and CB for hair loss. Some report maintenance and regrowth with Pyri, while others find limited success with RU58841 and switch to combinations like finasteride and minoxidil or minoxidil and dutasteride.

community The Real Cause Of Androgenetic Alopecia

675 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

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Learn

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn Pyrilutamide

Experimental topical anti-androgen, also known as KX-826

learn RU58841

Experimental topical anti-androgen sold as a research chemical

learn Saw Palmetto

Palm-berry extract taken as a supplement

Is saw palmetto good for androgenetic alopecia or only for mild hair loss? Evidence is weak and mostly in men with mild to moderate hair loss. In the one comparison study, fewer men improved on saw palmetto than on finasteride.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Argan oil

Argan oil: Is it useful for androgenic alopecia, or just for making hair look nice? Argan oil primarily improves hair appearance but lacks proven effectiveness for androgenic alopecia.

learn Verteporfin

Is Verteporfin effective for both androgenic alopecia and alopecia areata? Verteporfin has never been tested in people with pattern hair loss or alopecia areata. It is an eye drug with only mouse wound data behind the hair interest.

learn Vitamin B5

Does Vitamin B5 prevent DHT-related androgenic alopecia? There is no evidence that vitamin B5 prevents DHT-related androgenic alopecia; no human trial has tested it for this.

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